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Centella Asiatica (Gotu Kola)

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Centella Asiatica (Gotu Kola). Traditional brain and skin tonic — supports cognition and wound healing.

How it works. Asiaticosides upregulate collagen synthesis and BDNF.

What the research supports. 2 graded claims. Strongest: Improves wound healing and scarring (moderate).

How much to take. Typical dose: 500–1000 mg.

Side effects and interactions. 1 medication interaction listed. Serious: Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Forms. 1 forms. Pick one to open its profile.

Key studies. 9 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Centella Asiatica (Gotu Kola). Anecdotes are not medical advice.

Centella Asiatica (Gotu Kola). Traditional brain and skin tonic — supports cognition and wound healing.

Key compound: asiatic acidC30H48O5 · 488.7 g/mol

What it is

Traditional brain and skin tonic — supports cognition and wound healing.

Food sources

Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice

Goals

MemoryAnxiety SupportSkin HealthCollagen Production

How it works

Asiaticosides upregulate collagen synthesis and BDNF.

Pathways

  • Asiaticosides upregulate collagen synthesis

Effects

  • +wound healing and scarring supports
  • +Mild anxiolytic supports

What the research supports

Improves wound healing and scarringmoderate
Mild anxiolyticlimited

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
500–1000 mg
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodOptional
Best formMost evidence is based on the standardized extract capsule form.
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Side effects & interactions

Common side effects

  • Centella Asiatica (Gotu Kola) is generally well-tolerated at evidence-based doses
  • Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
  • Headache or transient fatigue reported by a small fraction of users

Serious

  • Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing

Medication interactions

Prescription medications (general)minor

Always disclose Centella Asiatica (Gotu Kola) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Key studies

9 studies cited in total.

PubMed: Centella Asiatica (Gotu Kola) — Improves wound healing and scarring ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Centella Asiatica (Gotu Kola) and "Improves wound healing and scarring". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Centella Asiatica (Gotu Kola) — Mild anxiolytic ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Centella Asiatica (Gotu Kola) and "Mild anxiolytic". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Centella Asiatica (Gotu Kola) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Centella Asiatica (Gotu Kola) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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