SYS ONLINE
← Categories

Andropause Support

Age-related male hormone decline.

Ranked by evidence strength across reported benefits.

Herb#1· strong

Ashwagandha

Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.

Vitamin#2· strong

Vitamin D3

Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.

Herb#3· strong

Tribulus Terrestris

Traditionally used for libido; testosterone-boosting claims not supported by trials.

Herb#4· moderate

Tongkat Ali

Malaysian root extract that frees bound testosterone via SHBG reduction.

Mineral#5· moderate

Zinc

Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.

Herb#6· moderate

Fenugreek

Spice/herb traditionally for libido & glycemic control; modest free-T effects.

Herb#7· moderate

Mucuna Pruriens

Natural L-DOPA source studied for mood, libido, and Parkinson's.

Compound#8· moderate

DHEA

Adrenal androgen precursor declining with age; used for adrenal insufficiency and aging.

Herb#9· moderate

Tongkat Ali (Eurycoma longifolia)

Malaysian root with moderate human evidence for raising free testosterone and reducing SHBG.

Compound#10· moderate

Yohimbine

Alpha-2 antagonist — improves erection and fat loss in fasted state but cardiovascular caution.

Herb#11· moderate

KSM-66 Ashwagandha

Root-only standardized ashwagandha extract — the most-studied form for stress and T-support.

Compound#12· moderate

Shilajit

Himalayan mineral exudate rich in fulvic acid, studied for testosterone and fatigue.

Compound#13· moderate

DIM (Diindolylmethane)

Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.

Herb#14· moderate

Saw Palmetto

5α-reductase-inhibiting berry extract — used for BPH and androgenic hair loss.

Compound#15· moderate

DIM (Diindolylmethane)

Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.

Herb#16· moderate

Saw Palmetto

Lipidosterolic extract used for BPH urinary symptoms.

Herb#17· moderate

Pygeum

African plum bark used for BPH urinary symptoms.

Herb#18· moderate

Stinging Nettle Root

Herbal for BPH and SHBG modulation, often paired with saw palmetto.

Herb#19· moderate

Panax Ginseng (Sexual Health)

Korean red ginseng with RCT-level evidence for erectile dysfunction.

Mineral#20· moderate

Zinc (Sperm Health)

Concentrated in semen — essential for sperm production and testosterone.

Herb#21· moderate

Tongkat Ali (Physta)

Water-extracted standardized tongkat ali for testosterone and stress.

Compound#22· moderate

Icariin (Horny Goat Weed)

Active flavonoid from Epimedium acting as PDE5 inhibitor.

Compound#23· moderate

Lycopene

Tomato carotenoid linked with prostate and cardiovascular protection.

Herb#24· moderate

Ashwagandha (Strength)

KSM-66 dose for resistance training adaptations.

Mineral#25· moderate

Boron (Extra)

Trace mineral that modulates steroid hormones and bone.

Compound#26· moderate

Shilajit (Fulvic-Standardized)

Himalayan mineral pitch with fulvic acids studied for testosterone.

Herb#27· moderate

Mucuna Pruriens

Velvet bean providing natural L-DOPA.

Herb#28· moderate

Nettle Root

Urtica dioica for BPH.

Compound#29· moderate

Beta-Sitosterol

Plant sterol for BPH and cholesterol.

Herb#30· moderate

Black Maca

Lepidium meyenii black variant for energy.

Herb#31· moderate

Red Maca

Lepidium meyenii red variant for prostate.

Compound#32· moderate

Pomegranate Extract

Punica granatum ellagitannins.

Herb#33· moderate

Tongkat Ali Eurycomanone-Standardized

LJ100 standardized to 22% eurypeptides.

Herb#34· moderate

Stinging Nettle Root

Urtica dioica root for free testosterone.

Mineral#35· moderate

Boron Citrate

Boron for hormone modulation.

Mineral#36· moderate

Zinc Monomethionine (ZMA)

Zinc + magnesium + B6 for recovery.

Mineral#37· limited

Boron

Trace mineral implicated in steroid hormone metabolism and bone integrity.

Compound#38· limited

Pumpkin Seed Oil

Cold-pressed seed oil studied for hair density and prostate health.

Mineral#39· limited

Boron

Trace mineral with modest effects on free testosterone and bone mineralization.

Herb#40· limited

Cistanche Tubulosa

Desert plant tonic for libido and cognition.

Herb#41· limited

Fadogia Agrestis

Nigerian shrub — popularized for testosterone support; sparse human data.

Herb#42· limited

Horny Goat Weed

PDE5-inhibiting flavonoid (icariin) used for libido and erectile support.

Herb#43· limited

Horny Goat Weed (Epimedium)

Icariin-rich herb with PDE5-inhibitor-like activity for erectile function.

Mineral#44· limited

Zinc Picolinate

Zinc chelated to picolinic acid — one of the most bioavailable oral forms.

Herb#45· limited

Pine Pollen

Phyto-androgen pollen containing trace testosterone and DHEA.

Herb#46· limited

Topical Saw Palmetto

Topical lotion form for androgenetic alopecia.

Herb#47· limited

Fadogia Agrestis

African shrub touted for testosterone (rodent data only).

Herb#48· anecdotal

Fadogia Agrestis

African shrub popularized for testosterone; limited human data and toxicology concerns.

Herb#49· anecdotal

Tongkat Ali (LJ100)

See main Tongkat Ali entry — kept here as placeholder, removed.