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DHT Management

5α-reductase modulation and scalp/prostate DHT.

Ranked by evidence strength across reported benefits.

Vitamin#1· strong

Biotin (B7)

Coenzyme for carboxylases — popular for hair and nails despite weak data outside true deficiency.

Herb#2· moderate

Tongkat Ali

Malaysian root extract that frees bound testosterone via SHBG reduction.

Mineral#3· moderate

Zinc

Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.

Herb#4· moderate

Tongkat Ali (Eurycoma longifolia)

Malaysian root with moderate human evidence for raising free testosterone and reducing SHBG.

Compound#5· moderate

Yohimbine

Alpha-2 antagonist — improves erection and fat loss in fasted state but cardiovascular caution.

Compound#6· moderate

Shilajit

Himalayan mineral exudate rich in fulvic acid, studied for testosterone and fatigue.

Compound#7· moderate

DIM (Diindolylmethane)

Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.

Herb#8· moderate

Saw Palmetto

5α-reductase-inhibiting berry extract — used for BPH and androgenic hair loss.

Compound#9· moderate

MSM (Methylsulfonylmethane)

Bioavailable sulfur donor for joints, skin, and hair-keratin synthesis.

Compound#10· moderate

Marine Collagen Peptides

Hydrolyzed fish collagen — supplies glycine, proline, and bioactive di/tripeptides for skin and hair.

Compound#11· moderate

DIM (Diindolylmethane)

Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.

Herb#12· moderate

Saw Palmetto

Lipidosterolic extract used for BPH urinary symptoms.

Herb#13· moderate

Pygeum

African plum bark used for BPH urinary symptoms.

Herb#14· moderate

Stinging Nettle Root

Herbal for BPH and SHBG modulation, often paired with saw palmetto.

Herb#15· moderate

Panax Ginseng (Sexual Health)

Korean red ginseng with RCT-level evidence for erectile dysfunction.

Mineral#16· moderate

Zinc (Sperm Health)

Concentrated in semen — essential for sperm production and testosterone.

Compound#17· moderate

Lycopene

Tomato carotenoid linked with prostate and cardiovascular protection.

Mineral#18· moderate

Boron (Extra)

Trace mineral that modulates steroid hormones and bone.

Herb#19· moderate

Mucuna Pruriens

Velvet bean providing natural L-DOPA.

Herb#20· moderate

Nettle Root

Urtica dioica for BPH.

Compound#21· moderate

Beta-Sitosterol

Plant sterol for BPH and cholesterol.

Herb#22· moderate

Black Maca

Lepidium meyenii black variant for energy.

Herb#23· moderate

Red Maca

Lepidium meyenii red variant for prostate.

Compound#24· moderate

Pomegranate Extract

Punica granatum ellagitannins.

Herb#25· moderate

Tongkat Ali Eurycomanone-Standardized

LJ100 standardized to 22% eurypeptides.

Herb#26· moderate

Stinging Nettle Root

Urtica dioica root for free testosterone.

Mineral#27· moderate

Boron Citrate

Boron for hormone modulation.

Mineral#28· moderate

Zinc Monomethionine (ZMA)

Zinc + magnesium + B6 for recovery.

Compound#29· limited

Pumpkin Seed Oil

Cold-pressed seed oil studied for hair density and prostate health.

Mineral#30· limited

Boron

Trace mineral with modest effects on free testosterone and bone mineralization.

Herb#31· limited

Fadogia Agrestis

Nigerian shrub — popularized for testosterone support; sparse human data.

Herb#32· limited

Rosemary Oil (Topical)

Topical rosemary oil — comparable to 2% minoxidil for AGA in head-to-head trial.

Herb#33· limited

Horsetail Extract

Silica-rich herb traditionally used for hair, nail, and connective tissue support.

Compound#34· limited

Marine Protein Complex (AminoMar)

Proprietary marine-derived complex (AminoMar) clinically studied for thinning hair in women.

Herb#35· limited

Horny Goat Weed (Epimedium)

Icariin-rich herb with PDE5-inhibitor-like activity for erectile function.

Mineral#36· limited

Zinc Picolinate

Zinc chelated to picolinic acid — one of the most bioavailable oral forms.

Mineral#37· limited

Zinc Bisglycinate

Glycine-chelated zinc — high absorption and very gentle on the stomach.

Herb#38· limited

Pine Pollen

Phyto-androgen pollen containing trace testosterone and DHEA.

Herb#39· limited

Topical Saw Palmetto

Topical lotion form for androgenetic alopecia.

Herb#40· limited

Fadogia Agrestis

African shrub touted for testosterone (rodent data only).

Herb#41· anecdotal

Fadogia Agrestis

African shrub popularized for testosterone; limited human data and toxicology concerns.