Supplement Scholar
Goal area

Organ-Specific Health

Liver, kidney, lung, eye, gallbladder, bladder.

87 profiles, most-studied first
C5H9NO3S

Glycine + NAC (GlyNAC)

Co-supplementation of glycine and N-acetylcysteine that restores glutathione in older adults and improves multiple hallmarks of aging.

Compound14 studies
Mg

Magnesium

Essential cofactor in 300+ enzymatic reactions, from ATP production to muscle relaxation.

Mineral12 studies
C27H44O

Vitamin D3

Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.

Vitamin12 studies
C60H92O6

Omega-3 (EPA/DHA)

Marine long-chain omega-3s — the most-studied anti-inflammatory and cardiovascular nutrient.

Fatty Acid11 studies
C21H20O6

Curcumin

Yellow polyphenol from turmeric — anti-inflammatory and joint-supportive when properly bioavailable.

Herb10 studies
C5H9NO3S

N-Acetyl Cysteine (NAC)

Glutathione precursor with mucolytic, hepatoprotective, and psychiatric uses.

Amino Acid10 studies
C63H88CoN14O14P

Vitamin B12

Essential cobalamin for methylation, red blood cell formation, and myelin maintenance.

Vitamin10 studies
Zn

Zinc

Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.

Mineral10 studies
C25H24O12

Artichoke Leaf Extract

Choleretic herb — supports bile flow, gallbladder, and mild lipid lowering.

Herb9 studies
C40H52O4

Astaxanthin

Algal carotenoid that is the strongest membrane antioxidant; UV and eye protection.

Compound9 studies
C40H52O4

Astaxanthin

Algae-derived xanthophyll — most potent natural antioxidant; UV/eye/skin support.

Compound9 studies
C21H21O11+

Bilberry

Anthocyanin-rich berry traditionally used for night vision and vascular support.

Herb9 studies
C10H16N2O3S

Biotin (B7)

Coenzyme for carboxylases — popular for hair and nails despite weak data outside true deficiency.

Vitamin9 studies
C5H14NO+

Choline

Essential nutrient for cell membranes, methylation, and acetylcholine synthesis.

Compound9 studies
C15H12O8

Dihydromyricetin (DHM)

Flavonoid from Hovenia dulcis — accelerates alcohol clearance and blunts hangover symptoms.

Compound9 studies
C19H19N7O6

Folate (Vitamin B9)

One-carbon donor essential for DNA synthesis and neural tube development.

Vitamin9 studies
C10H17N3O6S

Glutathione

Master intracellular antioxidant; oral bioavailability depends on form.

Compound9 studies
C6H10O7

Hyaluronic Acid

Glycosaminoglycan supporting skin hydration and joint lubrication.

Compound9 studies
Fe

Iron

Oxygen-carrying mineral central to hemoglobin and cellular respiration.

Mineral9 studies
C40H56O2

Lutein & Zeaxanthin

Macular carotenoids that filter blue light and reduce AMD progression.

Compound9 studies
C25H22O10

Milk Thistle

Hepatoprotective herb with antioxidant and anti-fibrotic effects.

Herb9 studies
C25H22O10

Milk Thistle (Liver)

Silymarin — most-studied liver herb, used for ALD, NAFLD, and toxin protection.

Herb9 studies
C25H22O10

Milk Thistle (Silymarin)

Hepatoprotective flavonolignan — best-known liver herb, often used around alcohol exposure.

Herb9 studies
C5H9NO3S

NAC (Pre/Post Drinking Use)

Glutathione precursor — bolsters acetaldehyde detoxification before and after alcohol.

Amino Acid9 studies
K

Potassium

Major intracellular cation essential for BP control, muscle function, and acid-base balance.

Mineral9 studies
C5H10N2O2

Pumpkin Seed Oil

Cold-pressed seed oil studied for hair density and prostate health.

Compound9 studies
C15H22N6O5S

SAMe (S-Adenosyl Methionine)

Universal methyl donor with antidepressant and liver-supportive evidence.

Compound9 studies
C44H64O24

Saffron

Culinary spice with antidepressant effects comparable to SSRIs in mild-moderate depression.

Herb9 studies
C33H38N4O6

Spirulina

Blue-green algae — protein-rich with phycocyanin antioxidant and immune effects.

Compound9 studies
C6H11NOS2

Sulforaphane (Broccoli Sprout)

Most potent natural Nrf2 activator — upregulates phase II detox enzymes.

Compound9 studies
C26H45NO6S

TUDCA

Bile acid with hepatoprotective effects and ER stress reduction.

Compound9 studies
C20H30O

Vitamin A (Retinol)

Fat-soluble vitamin essential for vision, immune function, and epithelial integrity.

Vitamin9 studies
C12H17N4OS+

Vitamin B1 (Thiamine)

Cofactor for carbohydrate metabolism and nerve conduction.

Vitamin9 studies
C6H8O6

Vitamin C

Water-soluble antioxidant, collagen cofactor, and immune supporter.

Vitamin9 studies
C6H13NO2

Whey Protein

Fast-digesting complete protein rich in leucine for muscle protein synthesis.

Compound9 studies
C9H17NO4

ALCAR (Pre-Drinking)

Mitochondrial cofactor that may reduce acetaldehyde-induced oxidative stress.

Amino Acid8 studies
C22H32O2

Algal Omega-3 (Vegan EPA/DHA)

Plant-based EPA and DHA from microalgae for vegan diets.

Fatty Acid8 studies
C25H24O12

Artichoke Leaf

Cholagogue herb improving dyspepsia and modestly reducing cholesterol.

Herb8 studies
C40H52O4

Astaxanthin (Haematococcus)

Algae carotenoid antioxidant.

Compound8 studies
C41H68O14

Astragalus

TCM tonic with immune-stimulating and CKD-supportive evidence.

Herb8 studies
C55H72MgN4O5

Barley Grass Powder

Hordeum vulgare young leaves.

Compound8 studies
C21H21O11+

Bilberry Anthocyanins

Vaccinium myrtillus for eye health.

Herb8 studies
C21H21O11+

Blackcurrant Anthocyanins

Anthocyanin-rich berry extract for night vision and eye fatigue.

Compound8 studies
Ca

Calcium

Major bone mineral; also critical for muscle contraction and nerve signaling.

Mineral8 studies
C6H10O8

Calcium D-Glucarate

Beta-glucuronidase inhibitor promoting elimination of conjugated hormones/toxins.

Compound8 studies
C55H72MgN4O5

Chlorella

Green algae with chlorophyll.

Compound8 studies
C9H19NO7

Choline Bitartrate

Affordable choline source — supports phospholipid synthesis and methylation.

Compound8 studies
C22H32O2

Cod Liver Oil

Traditional A, D, omega-3 source.

Fatty Acid8 studies
Cu

Copper

Trace mineral cofactor for ceruloplasmin and connective tissue crosslinking.

Mineral8 studies
C4H8CuN2O4

Copper Bisglycinate

Chelated copper used to balance high-dose zinc supplementation.

Mineral8 studies
C30H24O12

Cranberry

Berry with PACs that inhibit E. coli adhesion to urothelium for UTI prevention.

Herb8 studies
C30H24O12

Cranberry (PAC-A)

Type-A proanthocyanidins prevent E. coli adhesion to bladder epithelium.

Compound8 studies
C6H12O6

D-Mannose

Simple sugar that binds E. coli fimbriae, flushing them from the urinary tract.

Compound8 studies
C22H32O2

DHA-Dominant Fish Oil

High-DHA for brain health.

Fatty Acid8 studies
C9H15N3O2S

Ergothioneine

Unique antioxidant from mushrooms with its own transporter — accumulates in oxidative-stress tissues.

Compound8 studies
C20H23N7O7

Folinic Acid (Leucovorin)

Reduced folate form.

Vitamin8 studies

Heme Iron Polypeptide

Heme iron from bovine blood.

Mineral8 studies
C19H30O5

Idebenone

Synthetic CoQ10 analog with better water solubility; used in LHON.

Compound8 studies
I2

Iodine

Halogen essential for thyroid hormone synthesis.

Mineral8 studies
C9H14N4O3

L-Carnosine

Dipeptide that buffers protons and reduces advanced glycation end-products.

Amino Acid8 studies
C6H9N3O2

L-Histidine

Conditionally essential amino acid for hemoglobin.

Amino Acid8 studies
C5H12N2O2

L-Ornithine

Urea cycle amino acid for ammonia clearance.

Amino Acid8 studies
C12H22O11

Lactulose

Non-absorbable disaccharide for constipation and HE.

Compound8 studies
C40H56O2

Lutein

Macular xanthophyll for eye health.

Compound8 studies
Mn

Manganese

Trace mineral cofactor for SOD, gluconeogenesis, and bone formation.

Mineral8 studies
Mo

Molybdenum

Trace mineral cofactor for xanthine oxidase and sulfite oxidase.

Mineral8 studies
C14H17NO5S

Moringa Oleifera

Drumstick tree leaf for nutrition.

Herb8 studies
C5H9NO3S

NAC (Lung Support)

Mucolytic and antioxidant — used for COPD exacerbations and idiopathic pulmonary fibrosis.

Amino Acid8 studies
C24H40O5

Ox Bile Extract

Replacement bile salts for post-cholecystectomy or biliary insufficiency.

Compound8 studies

Phosphatidylcholine

Membrane phospholipid for liver.

Compound8 studies

Phosphatidylcholine (PC)

Major brain and hepatic phospholipid often given for liver support.

Compound8 studies
C24H28O11

Picrorhiza Kurroa

Indian herb for liver protection.

Herb8 studies
C6H7K3O8

Potassium Citrate

Alkalinizing K salt used for kidney stone prevention and bone health.

Mineral8 studies
IK

Potassium Iodide

Iodine source for thyroid hormone.

Mineral8 studies
C18H32O16

Prebiotics (Inulin, FOS, GOS)

Fermentable fibers feeding beneficial gut bacteria.

Compound8 studies
C24H32O7

Schisandra

Adaptogenic berry traditionally used for stamina, liver protection, and stress resilience.

Herb8 studies
C25H22O10

Siliphos (Silybin Phytosome)

Silybin-phosphatidylcholine complex.

Herb8 studies
C25H22O10

Silybin

Most active milk thistle flavonolignan.

Compound8 studies
C25H22O10

Silymarin (Milk Thistle)

Silybum marianum flavonolignans for liver.

Herb8 studies

Soy Lecithin

Phosphatidylcholine source.

Compound8 studies
C5H11NO2

Trimethylglycine (Betaine)

Same as TMG; osmolyte and methyl donor.

Compound8 studies
C12H16O7

Uva-Ursi

Antibacterial herb for acute uncomplicated UTI; alkaline urine required.

Herb8 studies
C9H17NO5

Vitamin B5 (Pantothenic acid)

Component of coenzyme A, central to fatty acid and acetylcholine synthesis.

Vitamin8 studies
C27H44O

Vitamin D3 + K2 Synergy Note

Combined fat-soluble vitamins addressing calcium destination (bone vs artery).

Vitamin8 studies
C31H46O2

Vitamin K1 (Phylloquinone)

Leafy-green K1 essential for hepatic coagulation factors.

Vitamin8 studies
C55H72MgN4O5

Wheatgrass

Young wheat shoots.

Compound8 studies
C40H56O2

Zeaxanthin

Macular xanthophyll partner to lutein.

Compound8 studies