Molybdenum
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Molybdenum. Trace mineral cofactor for xanthine oxidase and sulfite oxidase.
How it works. Cofactor (Moco) for xanthine oxidase, aldehyde oxidase, and sulfite oxidase.
What the research supports. 1 graded claims. Strongest: Prevents sulfite-induced reactions in deficiency (moderate).
How much to take. Typical dose: 45 mcg.
Side effects and interactions. 1 medication interaction listed. Serious: Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing.
Stacking. Pairs well with Milk thistle (silymarin), NAC.
Forms. 1 forms. Pick one to open its profile.
Key studies. 8 studies cited. The strongest are listed with links to PubMed.
Community. Experiences from people who have tried Molybdenum. Anecdotes are not medical advice.
Molybdenum. Trace mineral cofactor for xanthine oxidase and sulfite oxidase.
What it is
Trace mineral cofactor for xanthine oxidase and sulfite oxidase.
Food sources
Goals
How it works
Cofactor (Moco) for xanthine oxidase, aldehyde oxidase, and sulfite oxidase.
Pathways
- Sulfur metabolism
- Purine catabolism
Effects
- +Sulfite detoxification supports
What the research supports
Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.
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Side effects & interactions
Common side effects
- Molybdenum is generally well-tolerated at evidence-based doses
- Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- Headache or transient fatigue reported by a small fraction of users
Serious
- Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Medication interactions
Always disclose Molybdenum use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
Check any supplement–medication combination with your pharmacist before starting.
Combines with
Pairs well
- Milk thistle (silymarin)Complementary hepatoprotective antioxidant pathways.
- NACRestores hepatic glutathione.
Forms
Key studies
8 studies cited in total.
Opens current human and preclinical literature matching Molybdenum and "Prevents sulfite-induced reactions in deficiency". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Molybdenum and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Molybdenum and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
Discussion
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