Supplement Scholar
Mineral

Potassium Iodide

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Potassium Iodide. Iodine source for thyroid hormone.

How it works. Substrate for thyroglobulin iodination.

What the research supports. 1 graded claims. Strongest: Prevents goiter (moderate).

How much to take. Typical dose: 150 mcg.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Common forms. Available as Chelated form (glycinate, bisglycinate, citrate, malate), Inorganic salt (oxide, sulfate, chloride), Liquid ionic solution, Topical or transdermal preparation.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Potassium Iodide. Anecdotes are not medical advice.

Potassium Iodide. Iodine source for thyroid hormone.

Molecular structureIK · 166.0028 g/mol

What it is

Iodine source for thyroid hormone.

Food sources

Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)Fortified foods such as cereals, breads, plant milks, and table saltMineral supplements as chelates, citrates, glycinates, or inorganic salts

Goals

Hormone BalanceGeneral Wellness

How it works

Substrate for thyroglobulin iodination.

Pathways

  • Substrate for thyroglobulin iodination

Effects

  • ↓goiter decreases

What the research supports

Prevents goitermoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
150 mcg
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the chelated form (glycinate, bisglycinate, citrate, malate) form.
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Side effects & interactions

Common side effects

  • Thyroid dysfunction at high doses

Medication interactions

Prescription medications (general)minor

Always disclose Potassium Iodide use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Common forms

  • Chelated form (glycinate, bisglycinate, citrate, malate)
  • Inorganic salt (oxide, sulfate, chloride)
  • Liquid ionic solution
  • Topical or transdermal preparation

Key studies

8 studies cited in total.

PubMed: Potassium Iodide — Prevents goiter ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Potassium Iodide and "Prevents goiter". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Potassium Iodide — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Potassium Iodide and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Potassium Iodide — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Potassium Iodide and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

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