Cranberry
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Cranberry. Berry with PACs that inhibit E. coli adhesion to urothelium for UTI prevention.
How it works. A-type proanthocyanidins prevent fimbrial adhesion of E. coli.
What the research supports. 1 graded claims. Strongest: Reduces recurrent UTI in women (moderate).
How much to take. Typical dose: 36 mg PAC standardized, daily.
Side effects and interactions. 1 medication interaction listed. Serious: Kidney stones (high oxalate).
Stacking. Pairs well with Vitamin D3 + K2, Zinc.
Common forms. Available as Standardized PAC capsule, Juice (unsweetened).
Key studies. 8 studies cited. The strongest are listed with links to PubMed.
Community. Experiences from people who have tried Cranberry. Anecdotes are not medical advice.
Cranberry. Berry with PACs that inhibit E. coli adhesion to urothelium for UTI prevention.
What it is
Berry with PACs that inhibit E. coli adhesion to urothelium for UTI prevention.
Also called
Food sources
Goals
How it works
A-type proanthocyanidins prevent fimbrial adhesion of E. coli.
Pathways
- Bacterial anti-adhesion
Effects
- ↓UTI recurrence decreases
What the research supports
Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.
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Side effects & interactions
Common side effects
- GI upset
Serious
- Kidney stones (high oxalate)
Medication interactions
May increase INR.
Check any supplement–medication combination with your pharmacist before starting.
Combines with
Pairs well
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
Common forms
- Standardized PAC capsule
- Juice (unsweetened)
Key studies
8 studies cited in total.
Reduced UTI risk in women with recurrent UTIs and children.
Opens current human and preclinical literature matching Cranberry and "Reduces recurrent UTI in women". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Cranberry and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
Discussion
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