Sleep & Recovery
Sleep architecture, circadian, and CNS recovery.
Creatine Monohydrate
The most-studied and effective ergogenic aid — replenishes ATP via the phosphocreatine system.
Magnesium
Essential cofactor in 300+ enzymatic reactions, from ATP production to muscle relaxation.
Ashwagandha
Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.
Melatonin
Pineal hormone that signals biological night — most effective for circadian-rhythm shifts.
Glycine
Inhibitory neurotransmitter that improves sleep quality and supports collagen synthesis.
L-Theanine
Calm focus — alpha-wave amino acid from green tea that takes the edge off caffeine.
5-HTP
Direct serotonin precursor with mood and sleep applications.
Alpha-Lipoic Acid (ALA)
Universal antioxidant that's both water and fat soluble — supports glycemic control and nerve health.
B-Complex (Drinking Recovery)
Alcohol depletes B1, B6, folate — repletion supports neurological recovery.
BCAAs
Branched-chain amino acids — leucine is the primary mTOR signal for muscle protein synthesis.
CBD (Cannabidiol)
Non-intoxicating cannabinoid studied for anxiety, sleep, and seizures.
Citicoline (CDP-Choline)
Phospholipid precursor with cytidine bonus — supports membranes and dopamine.
Dihydromyricetin (DHM)
Flavonoid from Hovenia dulcis — accelerates alcohol clearance and blunts hangover symptoms.
HMB
Leucine metabolite reducing muscle protein breakdown, useful in untrained/elderly populations.
Ipamorelin
Selective GH secretagogue researched for muscle and recovery; not FDA approved.
L-Glutamine
Most abundant amino acid; primary fuel for enterocytes and immune cells.
L-Theanine (Sleep)
Tea-derived amino acid that raises alpha brainwaves — relaxation without sedation.
L-Tyrosine (Dopamine Replenishment)
Catecholamine precursor — replenishes dopamine/norepinephrine pools after stimulant use.
MSM
Organic sulfur source studied for joint pain and exercise recovery.
Milk Thistle (Silymarin)
Hepatoprotective flavonolignan — best-known liver herb, often used around alcohol exposure.
NAC (Pre/Post Drinking Use)
Glutathione precursor — bolsters acetaldehyde detoxification before and after alcohol.
Passionflower
Mild anxiolytic and sleep aid with GABA-A modulation.
Reishi
Adaptogenic mushroom used for immune balance, sleep, and stress.
Rhodiola Rosea
Arctic adaptogen for mental fatigue, burnout, and stress resilience.
Tart Cherry (Montmorency)
Natural melatonin and anthocyanin source — improves sleep and reduces DOMS.
5-HTP (Post-MDMA Replenishment)
Serotonin precursor — used post-MDMA to support depleted 5-HT stores. Never combine same-day.
5-HTP (Sleep Use)
Serotonin → melatonin precursor — supports sleep onset and depth.
ALCAR (Pre-Drinking)
Mitochondrial cofactor that may reduce acetaldehyde-induced oxidative stress.
ALCAR + ALA (Mitochondrial Protection)
Mitochondrial antioxidant stack — popularized as harm-reduction adjunct for MDMA neuroprotection.
Alpha-GPC (Cholinergic Recovery)
Choline source — supports acetylcholine after stimulant-driven depletion.
Apigenin
Chamomile/parsley flavonoid — GABA-A modulator and CD38 inhibitor for sleep and NAD+.
Ashwagandha (Cortisol Lowering)
Validated cortisol-lowering adaptogen — ~28% reduction in chronically stressed adults.
BPC-157
Research peptide derived from gastric protein, studied for tendon and gut healing.
California Poppy
Mild sedative with anxiolytic and analgesic activity.
California Poppy
Eschscholzia californica for anxiety and insomnia.
Casein Protein
Slow-digesting milk protein providing sustained amino acid release, popular pre-sleep.
Chamomile
Gentle anxiolytic and sleep-supportive herb.
Collagen + Vitamin C (Tendon Protocol)
15 g hydrolyzed collagen + 50 mg vit C taken 60 min pre-rehab — Shaw 2017 protocol.
EAAs (Essential Amino Acids)
All 9 essential amino acids; superior to BCAAs alone for MPS.
EGCG (Green Tea Catechin)
Potent CYP/COMT-modulating antioxidant — popularized in MDMA harm-reduction stacks.
Electrolyte Mix (Drinking Protocol)
Sodium, potassium, and magnesium to offset alcohol-induced diuresis and hangover dehydration.
GABA
Primary inhibitory neurotransmitter; oral supplementation has limited CNS penetration.
Ginger Root (Zingiber officinale)
Anti-nausea root — useful for hangover nausea and acid reflux after drinking.
Glycine (Sleep Onset)
3 g pre-bed lowers core body temperature and improves subjective sleep.
Honokiol
Active magnolia compound.
Hops Extract
Bitter cone extract with mild sedative and phytoestrogenic effects.
Kudzu (Pueraria lobata)
Isoflavone-rich root — reduces alcohol craving and intake in human trials.
L-Glutamine (Gut Barrier)
Preferred fuel for enterocytes — supports intestinal barrier integrity.
L-Ornithine
Urea-cycle amino acid that lowers fatigue and supports nighttime GH release.
L-Tryptophan
Essential amino acid precursor to serotonin and melatonin.
Lavender Oil (Silexan)
Oral lavender essential oil with proven anxiolytic effect.
Lemon Balm
Mild anxiolytic with cognitive calming effects via GABA-T inhibition.
Lion's Mane (Neuroregeneration)
NGF-upregulating mushroom — included in post-use stacks for neurotrophic support.
Magnesium Glycinate
Bisglycinate chelate form of magnesium — gentle, well-absorbed, ideal for sleep.
Magnesium Glycinate (Pre-Stimulant Use)
Pre-loaded magnesium glycinate reduces jaw clenching and post-use muscle tension during stimulant/MDMA use.
Magnesium L-Threonate
Mg form designed for brain penetration; studied for cognition and sleep.
Magnolia Bark
GABAergic anxiolytic bark extract used for sleep and stress.
Melatonin (low-dose physiologic)
Endogenous sleep hormone; low doses (0.3–0.5 mg) typically outperform mega-doses.
Micellar Casein
Slow-digesting milk protein.
NAC (Post-Use Recovery)
GSH precursor — supports glutamatergic rebalancing and oxidative stress recovery after stimulant or psychedelic use.
PharmaGABA
Naturally fermented GABA.
Phenibut (caution)
GABA-B agonist with high abuse and dependence potential; restricted in many countries.
Poria Cocos
TCM mushroom for sleep and immunity.
Prickly Pear Extract (Opuntia ficus-indica)
Cactus extract — clinically studied for reducing hangover severity when taken before drinking.
Saffron Affron
Standardized saffron for mood.
Shoden Ashwagandha
35% withanolide glycoside Ashwagandha for sleep.
TB-500 (Thymosin Beta-4)
Synthetic thymosin β-4 fragment researched for tissue repair; not approved.
Valerian + Hops
Sleep blend.
Valerian Root
Sedative herb traditionally used for sleep onset and mild anxiety.
Valerian Root
GABAergic sedative herb — modest sleep onset benefit.
Valerian Root Extract
Valeriana officinalis for sleep.
Vitamin C (Harm-Reduction Antioxidant)
Water-soluble antioxidant — quenches dopamine quinone and other reactive metabolites.
Zinc Monomethionine (ZMA)
Zinc + magnesium + B6 for recovery.
Ziziphus (Jujube Seed)
Traditional Chinese seed extract for insomnia and anxiety.