Supplement Scholar
Mushroom

Poria Cocos

Buy on Amazon ↗

Affiliate link: we may earn a commission at no extra cost to you. Disclosures

Poria Cocos. TCM mushroom for sleep and immunity.

How it works. Pachymic acid anti-inflammatory.

What the research supports. 1 graded claims. Strongest: Sleep support (moderate).

How much to take. Typical dose: 1500 mg.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Magnesium glycinate, L-theanine, Vitamin D3 + K2.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Poria Cocos. Anecdotes are not medical advice.

Poria Cocos. TCM mushroom for sleep and immunity.

Key compound: pachymic acidC33H52O5 · 528.8 g/mol

What it is

TCM mushroom for sleep and immunity.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Sleep & RecoveryImmune Function

How it works

Pachymic acid anti-inflammatory.

Pathways

  • Pachymic acid anti-inflammatory

Effects

  • +Sleep support supports

What the research supports

Sleep supportmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
1500 mg
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the capsule or softgel form.
Shop Poria Cocos on Amazon ↗

As an Amazon Associate I earn from qualifying purchases. Look for USP, NSF or Informed Sport seals before you buy.

Side effects & interactions

Common side effects

  • Well tolerated

Medication interactions

Prescription medications (general)minor

Always disclose Poria Cocos use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Poria Cocos — Sleep support ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Poria Cocos and "Sleep support". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Poria Cocos — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Poria Cocos and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Poria Cocos — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Poria Cocos and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

Loading discussion…