Supplement Scholar
Fitness & Performance

Energy Production

Mitochondrial output and perceived energy.

46 profiles, most-studied first
C5H9NO3S

Glycine + NAC (GlyNAC)

Co-supplementation of glycine and N-acetylcysteine that restores glutathione in older adults and improves multiple hallmarks of aging.

Compound14 studies
C59H90O4

Coenzyme Q10

Mitochondrial electron carrier and lipid-soluble antioxidant.

Compound10 studies
C8H10N4O2

Coffee

Caffeine + polyphenol matrix with strong evidence for mortality and T2D reduction.

Compound10 studies
C7H15NO3

L-Carnitine

Shuttles long-chain fatty acids into mitochondria for β-oxidation.

Amino Acid10 studies
C14H19NO9S2

Maca

Andean root associated with libido improvement and energy without hormone changes.

Herb10 studies
C14H20O7

Rhodiola Rosea

Arctic adaptogen — reduces fatigue and improves mental performance under stress.

Herb10 studies
C63H88CoN14O14P

Vitamin B12

Essential cobalamin for methylation, red blood cell formation, and myelin maintenance.

Vitamin10 studies

B-Complex (Drinking Recovery)

Alcohol depletes B1, B6, folate — repletion supports neurological recovery.

Vitamin9 studies
C24H26N2O13

Beetroot Juice

Dietary nitrate source improving NO production, BP, and endurance performance.

Compound9 studies
C8H10N4O2

Caffeine

Adenosine antagonist with strong evidence for cognitive and physical performance.

Compound9 studies
C34H46O18

Eleuthero

Adaptogen used to support stamina, immune function, and stress resilience.

Herb9 studies
Fe

Iron

Oxygen-carrying mineral central to hemoglobin and cellular respiration.

Mineral9 studies
C9H11NO3

L-Tyrosine (Dopamine Replenishment)

Catecholamine precursor — replenishes dopamine/norepinephrine pools after stimulant use.

Amino Acid9 studies
C11H15N2O8P

NMN

NAD+ precursor similar to NR; bioavailability route debated.

Compound9 studies
C11H15N2O5+

Nicotinamide Riboside (NR)

NAD+ precursor with bioavailability and longevity research interest.

Compound9 studies
C42H72O14

Panax Ginseng

Adaptogenic ginseng studied for fatigue, cognition, and erectile function.

Herb9 studies
C14H20O7

Rhodiola Rosea

Arctic adaptogen for mental fatigue, burnout, and stress resilience.

Herb9 studies

Shilajit

Himalayan mineral exudate rich in fulvic acid, studied for testosterone and fatigue.

Compound9 studies
C2H7NO3S

Taurine

Conditionally essential amino acid involved in bile salt conjugation, osmoregulation, and cardiac function.

Amino Acid9 studies
C12H17N4OS+

Vitamin B1 (Thiamine)

Cofactor for carbohydrate metabolism and nerve conduction.

Vitamin9 studies
C8H10NO5P-2

Vitamin B6 (Pyridoxine)

Cofactor for >100 enzymes including neurotransmitter synthesis.

Vitamin9 studies
C15H22N4O2S2

Allithiamine

Garlic-derived fat-soluble thiamine.

Vitamin8 studies
C27H30O16

Bee Pollen

Pollen collected by bees.

Compound8 studies
C14H19NO9S2

Black Maca

Lepidium meyenii black variant for energy.

Herb8 studies
C10H13N5O3

Cordyceps

Medicinal fungus studied for aerobic capacity and immune modulation.

Mushroom8 studies
C10H13N5O3

Cordyceps Militaris

Cordycepin-rich mushroom for energy and exercise.

Mushroom8 studies

Heme Iron Polypeptide

Heme iron from bovine blood.

Mineral8 studies
C23H30N2O4

Kratom (caution)

Atypical opioid herb with stimulant low-dose and sedating high-dose effects; addiction risk.

Herb8 studies
C5H12N2O2

L-Ornithine

Urea-cycle amino acid that lowers fatigue and supports nighttime GH release.

Amino Acid8 studies
C9H11NO3

L-Tyrosine

Catecholamine precursor preserving cognition under stress and sleep deprivation.

Amino Acid8 studies
C9H11NO3

L-Tyrosine (Thyroid Substrate)

Amino acid substrate paired with iodine to form thyroid hormones.

Amino Acid8 studies

Methylcobalamin High-Dose

Active B12 form for neuropathy.

Vitamin8 studies
C15H15NO2S

Modafinil (Rx note)

Wakefulness-promoting Rx — listed for reference; not a supplement.

Compound8 studies
C9H13NO2

P-Synephrine (Bitter Orange)

Bitter orange alkaloid used as ephedrine-replacement fat burner.

Compound8 studies
C14H6N2O8

PQQ

Cofactor stimulating mitochondrial biogenesis (PGC-1α).

Compound8 studies
C14H6N2O8

PQQ (Pyrroloquinoline Quinone)

Redox cofactor for mitochondrial biogenesis.

Compound8 studies
C42H72O14

Panax Ginseng (Sexual Health)

Korean red ginseng with RCT-level evidence for erectile dysfunction.

Herb8 studies
C12H14N2O2

Phenylpiracetam

Racetam + phenethylamine moiety — stimulant-like nootropic with rapid tolerance.

Nootropic8 studies
C14H20O7

Rhodiola SHR-5

Standardized Rhodiola for fatigue.

Herb8 studies
C10H18O3

Royal Jelly

Queen bee secretion with 10-HDA.

Compound8 studies
C24H32O7

Schisandra

Adaptogenic berry traditionally used for stamina, liver protection, and stress resilience.

Herb8 studies
C32H46N8O6S2

Sulbutiamine

Lipid-soluble thiamine derivative crossing the BBB for fatigue and focus.

Nootropic8 studies
C27H44O7

Suma Root

Brazilian ginseng adaptogen.

Herb8 studies
C17H20N4O6

Vitamin B2 (Riboflavin)

FAD/FMN precursor central to redox reactions and migraine prophylaxis.

Vitamin8 studies
C9H17NO5

Vitamin B5 (Pantothenic acid)

Component of coenzyme A, central to fatty acid and acetylcholine synthesis.

Vitamin8 studies
C16H18O9

Yerba Mate

South American caffeine-containing tea with saponin and chlorogenic acid content.

Herb8 studies