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Maca

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Maca. Andean root associated with libido improvement and energy without hormone changes.

How it works. Mechanism unclear; does not change testosterone or estrogen significantly.

What the research supports. 3 graded claims. Strongest: Improves sexual desire (moderate).

How much to take. Typical dose: 1.5–3 g/d.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Common forms. Available as Black, red, yellow maca, Gelatinized maca.

Key studies. 10 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Maca. Anecdotes are not medical advice.

Maca. Andean root associated with libido improvement and energy without hormone changes.

Key compound: benzyl glucosinolateC14H19NO9S2 · 409.4 g/mol

What it is

Andean root associated with libido improvement and energy without hormone changes.

Also called

Lepidium meyenii

Food sources

Lepidium meyenii root

Goals

How it works

Mechanism unclear; does not change testosterone or estrogen significantly.

Pathways

  • Unknown (likely CNS)

Effects

  • +Libido (without hormone changes) supports
  • +Sperm parameters supports

What the research supports

Improves sexual desiremoderate
Improves sperm concentration/motilitymoderate
Reduces SSRI-induced sexual dysfunctionmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
1.5–3 g/d
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the black, red, yellow maca form.
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Side effects & interactions

Common side effects

  • GI upset

Medication interactions

Prescription medications (general)minor

Always disclose Maca use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Common forms

  • Black, red, yellow maca
  • Gelatinized maca

Key studies

10 studies cited in total.

PubMed: Maca — Improves sexual desire ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Maca and "Improves sexual desire". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Maca — Improves sperm concentration/motility ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Maca and "Improves sperm concentration/motility". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Maca — Reduces SSRI-induced sexual dysfunction ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Maca and "Reduces SSRI-induced sexual dysfunction". Filter by RCT, meta-analysis, or year on the results page.

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