Hormones & Endocrine
Testosterone, estrogen, thyroid, cortisol, insulin & growth hormone.
Magnesium
Essential cofactor in 300+ enzymatic reactions, from ATP production to muscle relaxation.
Tongkat Ali
Malaysian root extract that frees bound testosterone via SHBG reduction.
Vitamin D3
Steroid hormone precursor regulating ~5% of the human genome — bone, immune, and hormonal health.
Ashwagandha
Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.
Fenugreek
Spice/herb traditionally for libido & glycemic control; modest free-T effects.
L-Theanine
Calm focus — alpha-wave amino acid from green tea that takes the edge off caffeine.
Rhodiola Rosea
Arctic adaptogen — reduces fatigue and improves mental performance under stress.
Zinc
Cofactor for ~300 enzymes — critical for testosterone, immune function, and DNA synthesis.
Berberine (Glucose Use)
AMPK activator with metformin-comparable glucose-lowering effects.
Boron
Trace mineral implicated in steroid hormone metabolism and bone integrity.
Chasteberry (Vitex)
Dopaminergic herb reducing prolactin and improving PMS/luteal phase symptoms.
Cistanche Tubulosa
Desert plant tonic for libido and cognition.
DHEA
Adrenal androgen precursor declining with age; used for adrenal insufficiency and aging.
DIM (Diindolylmethane)
Cruciferous-derived compound modulating estrogen metabolism toward 2-OH pathway.
DIM (Diindolylmethane)
Cruciferous-vegetable metabolite that shifts estrogen metabolism toward 2-OH (protective) pathways.
Eleuthero
Adaptogen used to support stamina, immune function, and stress resilience.
Guggul (Commiphora mukul)
Ayurvedic resin used historically for cholesterol and thyroid support.
Holy Basil (Tulsi)
Ayurvedic adaptogen with anti-stress, anti-inflammatory, and glycemic effects.
L-Arginine (GH Pulse)
Stimulates a transient growth hormone pulse when taken on an empty stomach.
Licorice Root
Adrenal-supporting herb; chronic high-dose causes pseudo-aldosteronism.
Metformin (Rx, reference)
Diabetes drug studied for longevity (TAME trial) via AMPK activation.
Mucuna Pruriens
Natural L-DOPA source studied for mood, libido, and Parkinson's.
Panax Ginseng
Adaptogenic ginseng studied for fatigue, cognition, and erectile function.
Phosphatidylserine (PS)
Phospholipid that supports cognition and may blunt cortisol response to stress.
Reishi
Adaptogenic mushroom used for immune balance, sleep, and stress.
Rhodiola Rosea
Arctic adaptogen for mental fatigue, burnout, and stress resilience.
Salvia officinalis (Sage)
Culinary sage with cholinergic and anti-hyperhidrosis effects.
Shilajit
Himalayan mineral exudate rich in fulvic acid, studied for testosterone and fatigue.
Tribulus Terrestris
Traditionally used for libido; testosterone-boosting claims not supported by trials.
Ashwagandha (Cortisol Lowering)
Validated cortisol-lowering adaptogen — ~28% reduction in chronically stressed adults.
Ashwagandha (Thyroid Support)
Supports T4→T3 conversion in subclinical hypothyroid adults.
Bacopa Monnieri
Ayurvedic nootropic with strong evidence for memory consolidation over 8–12 weeks.
Bladderwrack
Fucus vesiculosus seaweed for thyroid.
Boron Citrate
Boron for hormone modulation.
Calcium D-Glucarate
Beta-glucuronidase inhibitor promoting elimination of conjugated hormones/toxins.
Chaste Tree (Vitex)
Vitex agnus-castus for PMS.
D-Chiro-Inositol
Complementary inositol used in 40:1 myo-inositol ratio for PCOS.
Fadogia Agrestis
African shrub popularized for testosterone; limited human data and toxicology concerns.
Hops Extract
Bitter cone extract with mild sedative and phytoestrogenic effects.
Horny Goat Weed
PDE5-inhibiting flavonoid (icariin) used for libido and erectile support.
Icariin (Horny Goat Weed)
Active flavonoid from Epimedium acting as PDE5 inhibitor.
Iodine
Halogen essential for thyroid hormone synthesis.
Iodine (Thyroid Optimization)
Essential thyroid hormone substrate — careful dosing required in autoimmunity.
KSM-66 Ashwagandha Thyroid
Ashwagandha for subclinical hypothyroid.
Kelp Iodine
Brown seaweed iodine source.
L-Ornithine
Urea-cycle amino acid that lowers fatigue and supports nighttime GH release.
L-Tyrosine
Catecholamine precursor preserving cognition under stress and sleep deprivation.
L-Tyrosine (Thyroid Substrate)
Amino acid substrate paired with iodine to form thyroid hormones.
Lugol's Iodine
Strong iodine solution.
MK-677 (Ibutamoren) — Ref
Oral ghrelin mimetic that raises GH/IGF-1 (research reference).
Magnesium Glycinate
Bisglycinate chelate form of magnesium — gentle, well-absorbed, ideal for sleep.
Pine Pollen
Phyto-androgen pollen containing trace testosterone and DHEA.
Potassium Iodide
Iodine source for thyroid hormone.
Pregnenolone
Master steroid precursor; small doses studied for cognition and PTSD.
Royal Jelly
Queen bee secretion with 10-HDA.
Saw Palmetto
Lipidosterolic extract used for BPH urinary symptoms.
Schisandra
Adaptogenic berry traditionally used for stamina, liver protection, and stress resilience.
Selenium
Trace mineral essential for glutathione peroxidase and thyroid hormone activation.
Selenium (Selenomethionine)
Antioxidant trace element for thyroid.
Selenium-Iodine Synergy (note)
See individual selenium and iodine entries; balance is critical for thyroid health.
Stinging Nettle Root
Herbal for BPH and SHBG modulation, often paired with saw palmetto.
Stinging Nettle Root
Urtica dioica root for free testosterone.
Tesamorelin (Ref)
GHRH analog approved for HIV-associated visceral adiposity.
Tongkat Ali (LJ100)
See main Tongkat Ali entry — kept here as placeholder, removed.
Tongkat Ali Eurycomanone-Standardized
LJ100 standardized to 22% eurypeptides.
Zinc (Sperm Health)
Concentrated in semen — essential for sperm production and testosterone.