Cartilage Health
GAG and chondrocyte support.
Ranked by evidence strength across reported benefits.
Boswellia
Anti-inflammatory resin used for osteoarthritis and IBD.
Curcumin
Yellow polyphenol from turmeric — anti-inflammatory and joint-supportive when properly bioavailable.
Collagen Peptides
Hydrolyzed protein supplying glycine, proline, and hydroxyproline for connective tissue.
Hyaluronic Acid
Glycosaminoglycan supporting skin hydration and joint lubrication.
Bromelain
Pineapple proteolytic enzyme with anti-inflammatory and fibrinolytic effects.
Hyaluronic Acid (Oral)
GAG concentrated in synovial fluid — improves joint comfort and skin hydration.
MSM
Organic sulfur source studied for joint pain and exercise recovery.
MSM (Methylsulfonylmethane)
Bioavailable sulfur donor for joints, skin, and hair-keratin synthesis.
Marine Collagen Peptides
Hydrolyzed fish collagen — supplies glycine, proline, and bioactive di/tripeptides for skin and hair.
Krill Oil
Phospholipid-bound EPA/DHA from Antarctic krill — includes astaxanthin antioxidant.
Glucosamine
Cartilage building block; sulfate form has evidence for OA pain reduction.
Chondroitin
Cartilage glycosaminoglycan used with glucosamine for joint support.
Krill Oil
Phospholipid-bound omega-3 with astaxanthin; better bioavailability than fish oil per gram.
Glucosamine
Amino sugar substrate for glycosaminoglycan synthesis in cartilage.
Chondroitin Sulfate
GAG component of cartilage matrix — combined with glucosamine for OA.
UC-II (Undenatured Collagen)
Type II collagen taken at low dose for immune-mediated joint tolerance.
Curcumin Phytosome (Meriva)
Phosphatidylcholine-complexed curcumin — ~29× higher bioavailability than standard extract.
Curcumin C3 + Piperine
Classic curcumin extract with black pepper extract — boosts bioavailability ~20× via UGT inhibition.
Silica (Silicon)
Trace element involved in collagen and connective tissue crosslinking.
Serrapeptase
Silkworm-derived proteolytic enzyme used for inflammation and fibrin breakdown.
BPC-157
Research peptide derived from gastric protein, studied for tendon and gut healing.
TB-500 (Thymosin Beta-4)
Synthetic thymosin β-4 fragment researched for tissue repair; not approved.