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evidence · mechanism · dose
Supplements/Compound

Spirulina

Blue-green algae — protein-rich with phycocyanin antioxidant and immune effects.

AntioxidantsImmune Function (alias)General Wellness

Overview

Blue-green algae — protein-rich with phycocyanin antioxidant and immune effects.

Natural sources
    Common forms

      Forms & variants of Spirulina

      Different chemical forms of Spirulina behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      High-dose
      Spirulina (Extra Profile)

      Cyanobacterium with phycocyanin for allergy and immunity.

      Mechanism of action

      Phycocyanin inhibits COX-2; rich in protein, B-vitamins, and trace minerals.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Lowers LDL and BP modestly

        Moderate evidence

        Reduces allergic rhinitis symptoms

        Limited evidence

        Potential side effects

        Common
          Rare
          • · Heavy metal contamination (untested brands)
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            1–10 g/d
            With food?
            Optional

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Spirulina
            Amazon
            Wide selection · fast shipping
            Compound
            Spirulina
            iHerb
            Global delivery · curated brands
            Compound
            Spirulina
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (9)

            Systematic reviewEvid Based Complement Alternat Med · 2011

            Spirulina platensis on immune and metabolic markers

            Karkos PD, et al.

            Review of spirulina clinical trials.

            Key findings

            Improvements in lipids, blood pressure, and allergic rhinitis.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — Lowers LDL and BP modestly

            Live PubMed search

            Live results for "Spirulina Lowers LDL and BP modestly" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "Lowers LDL and BP modestly". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — Reduces allergic rhinitis symptoms

            Live PubMed search

            Live results for "Spirulina Reduces allergic rhinitis symptoms" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "Reduces allergic rhinitis symptoms". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — randomized controlled trial

            Live PubMed search

            Live results for "Spirulina randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — meta-analysis

            Live PubMed search

            Live results for "Spirulina meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — pharmacokinetics

            Live PubMed search

            Live results for "Spirulina pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — safety adverse events

            Live PubMed search

            Live results for "Spirulina safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Spirulina — dose response

            Live PubMed search

            Live results for "Spirulina dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Spirulina and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Spirulina — clinical evidence

            Live Scholar search

            Cross-database citation index for Spirulina as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.