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evidence · mechanism · dose
Supplements/Compound

Spirulina (Extra Profile)

Cyanobacterium with phycocyanin for allergy and immunity.

Immune Function

Overview

Cyanobacterium with phycocyanin for allergy and immunity.

Natural sources
    Common forms

      Forms & variants of Spirulina

      Different chemical forms of Spirulina behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Spirulina

      Blue-green algae — protein-rich with phycocyanin antioxidant and immune effects.

      Mechanism of action

      Phycocyanin inhibits COX-2 and histamine release; antioxidant via free-radical scavenging.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces allergic rhinitis symptoms

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
        • · Phenylketonuria risk (phenylalanine)
        Serious

          Drug interactions

          No notable interactions reported.

          Safety & non-supplemental interactions

          Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

          Avoid with these conditions
          • ·Autoimmune disease (theoretical immune activation)
          Avoid / monitor with these medications
          • ·Immunosuppressants

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          2 g
          With food?
          With meals

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Compound
          Spirulina (E…
          Amazon
          Wide selection · fast shipping
          Compound
          Spirulina (E…
          iHerb
          Global delivery · curated brands
          Compound
          Spirulina (E…
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (8)

          RCTEur Arch Otorhinolaryngol · 2008

          Spirulina in allergic rhinitis

          Cingi C, et al.

          12-week DB-RCT in 127 allergic rhinitis patients.

          Key findings

          Significantly improved nasal symptom scores vs placebo.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Spirulina (Extra Profile) — Reduces allergic rhinitis symptoms

          Live PubMed search

          Live results for "Spirulina (Extra Profile) Reduces allergic rhinitis symptoms" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Spirulina (Extra Profile) and "Reduces allergic rhinitis symptoms". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Spirulina (Extra Profile) — randomized controlled trial

          Live PubMed search

          Live results for "Spirulina (Extra Profile) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Spirulina (Extra Profile) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Spirulina (Extra Profile) — meta-analysis

          Live PubMed search

          Live results for "Spirulina (Extra Profile) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Spirulina (Extra Profile) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Spirulina (Extra Profile) — pharmacokinetics

          Live PubMed search

          Live results for "Spirulina (Extra Profile) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Spirulina (Extra Profile) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Spirulina (Extra Profile) — safety adverse events

          Live PubMed search

          Live results for "Spirulina (Extra Profile) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Spirulina (Extra Profile) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Spirulina (Extra Profile) — dose response

          Live PubMed search

          Live results for "Spirulina (Extra Profile) dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Spirulina (Extra Profile) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Spirulina (Extra Profile) — clinical evidence

          Live Scholar search

          Cross-database citation index for Spirulina (Extra Profile) as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.