Overview
Cyanobacterium with phycocyanin for allergy and immunity.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Forms & variants of Spirulina
Different chemical forms of Spirulina behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Phycocyanin inhibits COX-2 and histamine release; antioxidant via free-radical scavenging.
- · Phycocyanin inhibits COX-2
- · histamine release
- · antioxidant via free-radical scavenging
Effects on the body
Organ system effects
Spirulina (Extra Profile) modulates innate and adaptive immune responses, including cytokine signaling and barrier function.
Evidence-based benefits
Reduces allergic rhinitis symptoms
Moderate evidencePotential side effects
- · GI upset
- · Phenylketonuria risk (phenylalanine)
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Spirulina in allergic rhinitis
Cingi C, et al.
12-week DB-RCT in 127 allergic rhinitis patients.
Significantly improved nasal symptom scores vs placebo.
PubMed: Spirulina (Extra Profile) — Reduces allergic rhinitis symptoms
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PubMed: Spirulina (Extra Profile) — randomized controlled trial
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PubMed: Spirulina (Extra Profile) — dose response
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Google Scholar: Spirulina (Extra Profile) — clinical evidence
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Cross-database citation index for Spirulina (Extra Profile) as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.