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Supplements/Compound

Spirulina (Extra Profile)

Cyanobacterium with phycocyanin for allergy and immunity.

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Overview

Cyanobacterium with phycocyanin for allergy and immunity.

Natural sources
  • Endogenously produced or biosynthesized molecule
  • Standardized pharmaceutical- or food-grade supplement
  • Combined with cofactors that improve absorption or activity
Common forms
  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Forms & variants of Spirulina

Different chemical forms of Spirulina behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Phycocyanin inhibits COX-2 and histamine release; antioxidant via free-radical scavenging.

Pathways
  • · Phycocyanin inhibits COX-2
  • · histamine release
  • · antioxidant via free-radical scavenging

Effects on the body

Decreases
allergic rhinitis symptoms

Organ system effects

Immune System

Spirulina (Extra Profile) modulates innate and adaptive immune responses, including cytokine signaling and barrier function.

Evidence-based benefits

Reduces allergic rhinitis symptoms

Moderate evidence

Potential side effects

Common
  • · GI upset
Rare
  • · Phenylketonuria risk (phenylalanine)
Serious

    Drug interactions

    Prescription medications (general)
    Always disclose Spirulina (Extra Profile) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
    minor

    Safety & non-supplemental interactions

    Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

    Avoid with these conditions
    • ·Autoimmune disease (theoretical immune activation)
    Avoid / monitor with these medications
    • ·Immunosuppressants

    Supplement interactions

    Pairs well with
    • Vitamin D3 + K2
      Foundational immune modulation.
    • Zinc
      Required cofactor for innate and adaptive immune function.
    Avoid combining with

    No specific avoidances listed.

    Dosing & bioavailability

    Typical dose
    2 g
    Best form
    Most evidence is based on the capsule or softgel form.
    Timing
    Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
    With food?
    With meals

    Where to buy

    Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

    Scientific evidence8Show studies
    RCTEur Arch Otorhinolaryngol · 2008

    Spirulina in allergic rhinitis

    Cingi C, et al.

    12-week DB-RCT in 127 allergic rhinitis patients.

    Key findings

    Significantly improved nasal symptom scores vs placebo.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Spirulina (Extra Profile) — Reduces allergic rhinitis symptoms

    Live PubMed search

    Live results for "Spirulina (Extra Profile) Reduces allergic rhinitis symptoms" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Spirulina (Extra Profile) and "Reduces allergic rhinitis symptoms". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Spirulina (Extra Profile) — randomized controlled trial

    Live PubMed search

    Live results for "Spirulina (Extra Profile) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Spirulina (Extra Profile) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Spirulina (Extra Profile) — meta-analysis

    Live PubMed search

    Live results for "Spirulina (Extra Profile) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Spirulina (Extra Profile) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Spirulina (Extra Profile) — pharmacokinetics

    Live PubMed search

    Live results for "Spirulina (Extra Profile) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Spirulina (Extra Profile) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Spirulina (Extra Profile) — safety adverse events

    Live PubMed search

    Live results for "Spirulina (Extra Profile) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Spirulina (Extra Profile) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Spirulina (Extra Profile) — dose response

    Live PubMed search

    Live results for "Spirulina (Extra Profile) dose response" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Spirulina (Extra Profile) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewGoogle Scholar · 1970

    Google Scholar: Spirulina (Extra Profile) — clinical evidence

    Live Scholar search

    Cross-database citation index for Spirulina (Extra Profile) as it relates to "clinical evidence".

    Key findings

    Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

    Open study
    Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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