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evidence · mechanism · dose
Supplements/Herb

Yerba Mate (Weight)

Polyphenol-caffeine extract used for appetite and energy.

Energy Production

Overview

Polyphenol-caffeine extract used for appetite and energy.

Natural sources
    Common forms

      Forms & variants of Yerba Mate

      Different chemical forms of Yerba Mate behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Yerba Mate

      South American caffeine-containing tea with saponin and chlorogenic acid content.

      Focus dose
      Yerba Mate (Focus)

      Polyphenolic stimulant alternative to coffee for focus.

      Mechanism of action

      Caffeine + chlorogenic acids enhance fat oxidation and reduce appetite via GLP-1.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces body fat over 12 weeks

        Moderate evidence

        Potential side effects

        Common
        • · Jitter
        • · Insomnia
        Rare
          Serious
          • · Possible esophageal cancer risk with hot drinking long-term

          Drug interactions

          No notable interactions reported.

          Safety & non-supplemental interactions

          Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

          Avoid if you are
          • ·Pregnant or breastfeeding (insufficient safety data)
          • ·Children under 18 (unless directed by a clinician)

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          1000 mg extract tid
          With food?
          Before meals

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Herb
          Yerba Mate (…
          Amazon
          Wide selection · fast shipping
          Herb
          Yerba Mate (…
          iHerb
          Global delivery · curated brands
          Herb
          Yerba Mate (…
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (8)

          RCTBMC Complement Altern Med · 2015

          Yerba mate for weight loss

          Kim SY, et al.

          12-week DB-RCT in 30 obese adults.

          Key findings

          Reduced body fat % and waist-to-hip ratio vs placebo.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Yerba Mate (Weight) — Reduces body fat over 12 weeks

          Live PubMed search

          Live results for "Yerba Mate (Weight) Reduces body fat over 12 weeks" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Yerba Mate (Weight) and "Reduces body fat over 12 weeks". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Yerba Mate (Weight) — randomized controlled trial

          Live PubMed search

          Live results for "Yerba Mate (Weight) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Yerba Mate (Weight) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Yerba Mate (Weight) — meta-analysis

          Live PubMed search

          Live results for "Yerba Mate (Weight) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Yerba Mate (Weight) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Yerba Mate (Weight) — pharmacokinetics

          Live PubMed search

          Live results for "Yerba Mate (Weight) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Yerba Mate (Weight) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Yerba Mate (Weight) — safety adverse events

          Live PubMed search

          Live results for "Yerba Mate (Weight) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Yerba Mate (Weight) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Yerba Mate (Weight) — dose response

          Live PubMed search

          Live results for "Yerba Mate (Weight) dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Yerba Mate (Weight) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Yerba Mate (Weight) — clinical evidence

          Live Scholar search

          Cross-database citation index for Yerba Mate (Weight) as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.