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evidence · mechanism · dose
Supplements/Herb

Yerba Mate (Focus)

Polyphenolic stimulant alternative to coffee for focus.

Brain & CognitiveEnergy Production

Overview

Polyphenolic stimulant alternative to coffee for focus.

Natural sources
    Common forms

      Forms & variants of Yerba Mate

      Different chemical forms of Yerba Mate behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Yerba Mate

      South American caffeine-containing tea with saponin and chlorogenic acid content.

      Weight protocol
      Yerba Mate (Weight)

      Polyphenol-caffeine extract used for appetite and energy.

      Mechanism of action

      Caffeine + theobromine + chlorogenic acids modulate adenosine and dopamine systems.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves cognitive performance with less jitter than coffee

        Moderate evidence

        Potential side effects

        Common
        • · Jitter
        • · Insomnia
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            1–2 cups brewed
            With food?
            Morning

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
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            Amazon
            Wide selection · fast shipping
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            iHerb
            Global delivery · curated brands
            Herb
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            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Systematic reviewNutrients · 2017

            Yerba mate and cognition

            Alkhatib A, Atcheson R

            Review of yerba mate trials.

            Key findings

            Consistent benefits on cognitive and metabolic markers.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Yerba Mate (Focus) — Improves cognitive performance with less jitter than coffee

            Live PubMed search

            Live results for "Yerba Mate (Focus) Improves cognitive performance with less jitter than coffee" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Yerba Mate (Focus) and "Improves cognitive performance with less jitter than coffee". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Yerba Mate (Focus) — randomized controlled trial

            Live PubMed search

            Live results for "Yerba Mate (Focus) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Yerba Mate (Focus) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Yerba Mate (Focus) — meta-analysis

            Live PubMed search

            Live results for "Yerba Mate (Focus) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Yerba Mate (Focus) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Yerba Mate (Focus) — pharmacokinetics

            Live PubMed search

            Live results for "Yerba Mate (Focus) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Yerba Mate (Focus) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Yerba Mate (Focus) — safety adverse events

            Live PubMed search

            Live results for "Yerba Mate (Focus) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Yerba Mate (Focus) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Yerba Mate (Focus) — dose response

            Live PubMed search

            Live results for "Yerba Mate (Focus) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Yerba Mate (Focus) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Yerba Mate (Focus) — clinical evidence

            Live Scholar search

            Cross-database citation index for Yerba Mate (Focus) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.