Overview
Reference strontium salt used as anti-osteoporotic drug.
- Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
- Fortified foods such as cereals, breads, plant milks, and table salt
- Mineral supplements as chelates, citrates, glycinates, or inorganic salts
- Chelated form (glycinate, bisglycinate, citrate, malate)
- Inorganic salt (oxide, sulfate, chloride)
- Liquid ionic solution
- Topical or transdermal preparation
Forms & variants of Strontium
Different chemical forms of Strontium behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Promotes osteoblastogenesis and inhibits osteoclast activity.
- · Promotes osteoblastogenesis
- · inhibits osteoclast activity
Effects on the body
Organ system effects
Strontium Ranelate (Ref) contributes to bone mineralization, osteoblast activity, or calcium-phosphate homeostasis.
Evidence-based benefits
Reduces vertebral fracture risk
Strong evidencePotential side effects
- · Diarrhea
- · DRESS syndrome
- · Increased CV risk
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Strontium Ranelate (Ref) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Strontium Ranelate (Ref) third party tested NSF
CapsulesPre-measured Strontium Ranelate (Ref) capsules — easiest for travel and consistent daily dosing without scoops or scales.Strontium Ranelate (Ref) capsules
PowderBulk unflavored Strontium Ranelate (Ref) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Strontium Ranelate (Ref) powder unflavored
Best sellersMost-purchased Strontium Ranelate (Ref) products on Amazon — a quick way to see what's reviewed widely before you commit.Strontium Ranelate (Ref) best sellerScientific evidence8Show studiesHide studies
SOTI trial of strontium ranelate
Meunier PJ, et al.
3-year DB-RCT in 1649 postmenopausal women.
Reduced vertebral fracture risk by 41%.
PubMed: Strontium Ranelate (Ref) — Reduces vertebral fracture risk
Live PubMed search
Live results for "Strontium Ranelate (Ref) Reduces vertebral fracture risk" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "Reduces vertebral fracture risk". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Strontium Ranelate (Ref) — randomized controlled trial
Live PubMed search
Live results for "Strontium Ranelate (Ref) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Strontium Ranelate (Ref) — meta-analysis
Live PubMed search
Live results for "Strontium Ranelate (Ref) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Strontium Ranelate (Ref) — pharmacokinetics
Live PubMed search
Live results for "Strontium Ranelate (Ref) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Strontium Ranelate (Ref) — safety adverse events
Live PubMed search
Live results for "Strontium Ranelate (Ref) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.
PubMed: Strontium Ranelate (Ref) — dose response
Live PubMed search
Live results for "Strontium Ranelate (Ref) dose response" across the PubMed/MEDLINE peer-reviewed index.
Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "dose response". Filter by RCT, meta-analysis, or year on the results page.
Google Scholar: Strontium Ranelate (Ref) — clinical evidence
Live Scholar search
Cross-database citation index for Strontium Ranelate (Ref) as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.