SYS ONLINE
SUPPLEMENT_SCHOLAR
evidence · mechanism · dose
Supplements/Mineral

Strontium Ranelate (Ref)

Reference strontium salt used as anti-osteoporotic drug.

Bone Health

Overview

Reference strontium salt used as anti-osteoporotic drug.

Natural sources
    Common forms

      Forms & variants of Strontium

      Different chemical forms of Strontium behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Strontium

      Trace element that displaces Ca in bone and was approved (ranelate) for osteoporosis.

      Mechanism of action

      Promotes osteoblastogenesis and inhibits osteoclast activity.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces vertebral fracture risk

        Strong evidence

        Potential side effects

        Common
        • · Diarrhea
        Rare
        • · DRESS syndrome
        Serious
        • · Increased CV risk

        Drug interactions

        No notable interactions reported.

        Supplement interactions

        Pairs well with

        None listed.

        Avoid combining with

        No specific avoidances listed.

        Dosing & bioavailability

        Typical dose
        Rx 2 g/day

        Where to buy

        Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

        Mineral
        Strontium Ra…
        Amazon
        Wide selection · fast shipping
        Mineral
        Strontium Ra…
        iHerb
        Global delivery · curated brands
        Mineral
        Strontium Ra…
        Thorne
        Practitioner-grade · NSF tested

        Scientific evidence (8)

        RCTN Engl J Med · 2004

        SOTI trial of strontium ranelate

        Meunier PJ, et al.

        3-year DB-RCT in 1649 postmenopausal women.

        Key findings

        Reduced vertebral fracture risk by 41%.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Strontium Ranelate (Ref) — Reduces vertebral fracture risk

        Live PubMed search

        Live results for "Strontium Ranelate (Ref) Reduces vertebral fracture risk" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "Reduces vertebral fracture risk". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Strontium Ranelate (Ref) — randomized controlled trial

        Live PubMed search

        Live results for "Strontium Ranelate (Ref) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Strontium Ranelate (Ref) — meta-analysis

        Live PubMed search

        Live results for "Strontium Ranelate (Ref) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Strontium Ranelate (Ref) — pharmacokinetics

        Live PubMed search

        Live results for "Strontium Ranelate (Ref) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Strontium Ranelate (Ref) — safety adverse events

        Live PubMed search

        Live results for "Strontium Ranelate (Ref) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Strontium Ranelate (Ref) — dose response

        Live PubMed search

        Live results for "Strontium Ranelate (Ref) dose response" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Strontium Ranelate (Ref) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewGoogle Scholar · 1970

        Google Scholar: Strontium Ranelate (Ref) — clinical evidence

        Live Scholar search

        Cross-database citation index for Strontium Ranelate (Ref) as it relates to "clinical evidence".

        Key findings

        Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

        Open study
        Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.