SYS ONLINE
SUPPLEMENT_SCHOLAR
evidence · mechanism · dose
Supplements/Herb

Sensoril Ashwagandha

Root + leaf extract standardized to ≥10% withanolides — higher potency, more sedating.

Cortisol ManagementSleep & RecoveryMood & Anxiety

Overview

Root + leaf extract standardized to ≥10% withanolides — higher potency, more sedating.

Natural sources
    Common forms

      Forms & variants of Ashwagandha

      Different chemical forms of Ashwagandha behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Ashwagandha

      Adaptogenic herb that down-regulates HPA-axis output — lowers cortisol, supports T in stressed men.

      KSM-66 (root extract)
      KSM-66 Ashwagandha

      Root-only standardized ashwagandha extract — the most-studied form for stress and T-support.

      Strength protocol (600 mg)
      Ashwagandha (Strength)

      KSM-66 dose for resistance training adaptations.

      Mechanism of action

      Higher withanolide content from combined root + leaf.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces stress and improves sleep quality

        Moderate evidence

        Potential side effects

        Common
        • · Sedation
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)
            Avoid / monitor with these medications
            • ·Alcohol, benzodiazepines, opioids, sedating antihistamines (additive CNS depression)

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            125–250 mg
            Timing
            Evening
            With food?
            Optional

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
            Sensoril Ash…
            Amazon
            Wide selection · fast shipping
            Herb
            Sensoril Ash…
            iHerb
            Global delivery · curated brands
            Herb
            Sensoril Ash…
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTJANA · 2008

            Sensoril ashwagandha for stress and quality of life

            Auddy B, et al.

            60-day RCT of Sensoril 125–250 mg.

            Key findings

            Improved stress, cortisol, and quality-of-life scores.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Sensoril Ashwagandha — Reduces stress and improves sleep quality

            Live PubMed search

            Live results for "Sensoril Ashwagandha Reduces stress and improves sleep quality" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Sensoril Ashwagandha and "Reduces stress and improves sleep quality". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Sensoril Ashwagandha — randomized controlled trial

            Live PubMed search

            Live results for "Sensoril Ashwagandha randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Sensoril Ashwagandha and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Sensoril Ashwagandha — meta-analysis

            Live PubMed search

            Live results for "Sensoril Ashwagandha meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Sensoril Ashwagandha and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Sensoril Ashwagandha — pharmacokinetics

            Live PubMed search

            Live results for "Sensoril Ashwagandha pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Sensoril Ashwagandha and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Sensoril Ashwagandha — safety adverse events

            Live PubMed search

            Live results for "Sensoril Ashwagandha safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Sensoril Ashwagandha and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Sensoril Ashwagandha — dose response

            Live PubMed search

            Live results for "Sensoril Ashwagandha dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Sensoril Ashwagandha and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Sensoril Ashwagandha — clinical evidence

            Live Scholar search

            Cross-database citation index for Sensoril Ashwagandha as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.