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Supplements/Compound

Psyllium Husk

aka Plantago ovata · Metamucil

Soluble fiber with strong evidence for cholesterol reduction and bowel regularity.

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Overview

Soluble fiber with strong evidence for cholesterol reduction and bowel regularity.

Natural sources
  • Plantago ovata seed husk
Common forms
  • Psyllium husk powder

Forms & variants of Psyllium Husk

Different chemical forms of Psyllium Husk behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Forms viscous gel; binds bile acids increasing cholesterol catabolism; bulks stool.

Pathways
  • · Bile acid binding
  • · Stool bulking

Effects on the body

Decreases
LDL cholesterol
Decreases
Postprandial glucose

Organ system effects

Cardiovascular

Lowers LDL ~7% at 10 g/d.

Digestive / Gut

Improves constipation and IBS.

Evidence-based benefits

Reduces LDL cholesterol

Strong evidence

Improves IBS & chronic constipation

Strong evidence

Potential side effects

Common
  • · Bloating
  • · Gas
Rare
  • · Choking if dry-swallowed
Serious
  • · Bowel obstruction if inadequate fluid

Drug interactions

Most oral medications
Reduces absorption — separate 2 h.
moderate

Supplement interactions

Pairs well with
  • Omega-3
    Anti-inflammatory cardiovascular synergy.
  • CoQ10
    Supports mitochondrial energetics in cardiac tissue.
Avoid combining with

No specific avoidances listed.

Dosing & bioavailability

Typical dose
5–10 g × 1–3/d with plenty of water
Best form
Most evidence is based on the psyllium husk powder form.
Timing
Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
With food?
With a meal containing fat for fat-soluble compounds; otherwise either.

Where to buy

Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

Scientific evidence9Show studies
Meta-analysisAm J Gastroenterol · 2014

Psyllium for constipation and IBS

Moayyedi P, et al.

Meta-analysis of soluble fiber in IBS.

Key findings

Psyllium improves IBS symptoms; insoluble fiber may worsen.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — Reduces LDL cholesterol

Live PubMed search

Live results for "Psyllium Husk Reduces LDL cholesterol" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "Reduces LDL cholesterol". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — Improves IBS & chronic constipation

Live PubMed search

Live results for "Psyllium Husk Improves IBS & chronic constipation" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "Improves IBS & chronic constipation". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — randomized controlled trial

Live PubMed search

Live results for "Psyllium Husk randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — meta-analysis

Live PubMed search

Live results for "Psyllium Husk meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — pharmacokinetics

Live PubMed search

Live results for "Psyllium Husk pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — safety adverse events

Live PubMed search

Live results for "Psyllium Husk safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Psyllium Husk — dose response

Live PubMed search

Live results for "Psyllium Husk dose response" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Psyllium Husk and "dose response". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewGoogle Scholar · 1970

Google Scholar: Psyllium Husk — clinical evidence

Live Scholar search

Cross-database citation index for Psyllium Husk as it relates to "clinical evidence".

Key findings

Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

Open study
Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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