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evidence · mechanism · dose
Supplements/Compound

Psyllium (Extra Profile)

Viscous fiber with strong LDL-lowering effect.

Blood Sugar Management

Overview

Viscous fiber with strong LDL-lowering effect.

Natural sources
    Common forms

      Forms & variants of Psyllium Husk

      Different chemical forms of Psyllium Husk behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Psyllium Husk

      Soluble fiber with strong evidence for cholesterol reduction and bowel regularity.

      Parent
      Psyllium Husk

      Viscous soluble fiber — lowers cholesterol, glucose, and supports regularity.

      Mechanism of action

      Binds bile acids → liver pulls cholesterol → LDL decreases.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Lowers LDL by ~7%

        Strong evidence

        Potential side effects

        Common
        • · Bloating
        Rare
          Serious
          • · Take separate from meds

          Drug interactions

          No notable interactions reported.

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          10 g/day, divided
          With food?
          With water

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Compound
          Psyllium (Ex…
          Amazon
          Wide selection · fast shipping
          Compound
          Psyllium (Ex…
          iHerb
          Global delivery · curated brands
          Compound
          Psyllium (Ex…
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (8)

          Meta-analysisAm J Clin Nutr · 2018

          Psyllium on lipids meta-analysis

          Jovanovski E, et al.

          Meta-analysis of 28 RCTs.

          Key findings

          Significant reductions in LDL-C, non-HDL-C and apo B.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Psyllium (Extra Profile) — Lowers LDL by ~7%

          Live PubMed search

          Live results for "Psyllium (Extra Profile) Lowers LDL by ~7%" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Psyllium (Extra Profile) and "Lowers LDL by ~7%". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Psyllium (Extra Profile) — randomized controlled trial

          Live PubMed search

          Live results for "Psyllium (Extra Profile) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Psyllium (Extra Profile) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Psyllium (Extra Profile) — meta-analysis

          Live PubMed search

          Live results for "Psyllium (Extra Profile) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Psyllium (Extra Profile) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Psyllium (Extra Profile) — pharmacokinetics

          Live PubMed search

          Live results for "Psyllium (Extra Profile) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Psyllium (Extra Profile) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Psyllium (Extra Profile) — safety adverse events

          Live PubMed search

          Live results for "Psyllium (Extra Profile) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

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          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Psyllium (Extra Profile) — dose response

          Live PubMed search

          Live results for "Psyllium (Extra Profile) dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Psyllium (Extra Profile) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Psyllium (Extra Profile) — clinical evidence

          Live Scholar search

          Cross-database citation index for Psyllium (Extra Profile) as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.