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Supplements/Compound

Psyllium (Extra Profile)

Viscous fiber with strong LDL-lowering effect.

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Overview

Viscous fiber with strong LDL-lowering effect.

Natural sources
  • Endogenously produced or biosynthesized molecule
  • Standardized pharmaceutical- or food-grade supplement
  • Combined with cofactors that improve absorption or activity
Common forms
  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Forms & variants of Psyllium Husk

Different chemical forms of Psyllium Husk behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Binds bile acids → liver pulls cholesterol → LDL decreases.

Pathways
  • · Binds bile acids → liver pulls cholesterol → LDL decreases

Effects on the body

Decreases
LDL by ~7%

Organ system effects

Evidence-based benefits

Lowers LDL by ~7%

Strong evidence

Potential side effects

Common
  • · Bloating
Rare
    Serious
    • · Take separate from meds

    Drug interactions

    Prescription medications (general)
    Always disclose Psyllium (Extra Profile) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
    minor

    Supplement interactions

    Pairs well with
    • A high-quality multivitamin
      Covers micronutrient cofactors that support most supplement pathways.
    • Omega-3 (EPA/DHA)
      Foundational anti-inflammatory support that complements most regimens.
    Avoid combining with

    No specific avoidances listed.

    Dosing & bioavailability

    Typical dose
    10 g/day, divided
    Best form
    Most evidence is based on the capsule or softgel form.
    Timing
    Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
    With food?
    With water

    Where to buy

    Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

    Scientific evidence8Show studies
    Meta-analysisAm J Clin Nutr · 2018

    Psyllium on lipids meta-analysis

    Jovanovski E, et al.

    Meta-analysis of 28 RCTs.

    Key findings

    Significant reductions in LDL-C, non-HDL-C and apo B.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Psyllium (Extra Profile) — Lowers LDL by ~7%

    Live PubMed search

    Live results for "Psyllium (Extra Profile) Lowers LDL by ~7%" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Psyllium (Extra Profile) and "Lowers LDL by ~7%". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Psyllium (Extra Profile) — randomized controlled trial

    Live PubMed search

    Live results for "Psyllium (Extra Profile) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Psyllium (Extra Profile) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Psyllium (Extra Profile) — meta-analysis

    Live PubMed search

    Live results for "Psyllium (Extra Profile) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Psyllium (Extra Profile) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Psyllium (Extra Profile) — pharmacokinetics

    Live PubMed search

    Live results for "Psyllium (Extra Profile) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Psyllium (Extra Profile) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Psyllium (Extra Profile) — safety adverse events

    Live PubMed search

    Live results for "Psyllium (Extra Profile) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Psyllium (Extra Profile) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewPubMed (NLM) · 1970

    PubMed: Psyllium (Extra Profile) — dose response

    Live PubMed search

    Live results for "Psyllium (Extra Profile) dose response" across the PubMed/MEDLINE peer-reviewed index.

    Key findings

    Opens current human and preclinical literature matching Psyllium (Extra Profile) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

    Open study
    Systematic reviewGoogle Scholar · 1970

    Google Scholar: Psyllium (Extra Profile) — clinical evidence

    Live Scholar search

    Cross-database citation index for Psyllium (Extra Profile) as it relates to "clinical evidence".

    Key findings

    Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

    Open study
    Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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