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evidence · mechanism · dose
Supplements/Compound

Bifidobacterium Probiotics

Dominant probiotic genus in the colon; supports immune and gut barrier.

Gut HealthImmune Function

Overview

Dominant probiotic genus in the colon; supports immune and gut barrier.

Natural sources
  • Yogurt
  • Kefir
Common forms
  • B. lactis
  • B. longum
  • B. infantis

Forms & variants of Bifidobacterium Probiotics

Different chemical forms of Bifidobacterium Probiotics behave differently. Browse each form's mechanism, bioavailability, and best-use context.

B. longum 1714 (psychobiotic)
Bifidobacterium longum 1714

Psychobiotic strain shown to reduce stress and improve memory.

Mechanism of action

Produces short-chain fatty acids, lowers colonic pH, modulates Treg cells.

Pathways
  • · SCFA production
  • · Treg induction

Effects on the body

Supports
Gut barrier
Supports
Immune tolerance

Organ system effects

Digestive / Gut

B. infantis 35624 improves IBS symptoms.

Evidence-based benefits

Improves IBS symptoms (B. infantis 35624)

Moderate evidence

Potential side effects

Common
  • · Gas
Rare
    Serious

      Drug interactions

      No notable interactions reported.

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid with these conditions
      • ·Autoimmune disease (theoretical immune activation)
      Avoid / monitor with these medications
      • ·Immunosuppressants

      Supplement interactions

      Pairs well with

      None listed.

      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      1–10 billion CFU/d

      Where to buy

      Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Compound
      Bifidobacter…
      Amazon
      Wide selection · fast shipping
      Compound
      Bifidobacter…
      iHerb
      Global delivery · curated brands
      Compound
      Bifidobacter…
      Thorne
      Practitioner-grade · NSF tested

      Scientific evidence (8)

      RCTAm J Gastroenterol · 2006

      Bifidobacterium for IBS: a systematic review

      Whorwell PJ, et al.

      4-week RCT of B. infantis 35624 in IBS.

      Key findings

      Significant symptom improvement vs placebo.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Bifidobacterium Probiotics — Improves IBS symptoms

      Live PubMed search

      Live results for "Bifidobacterium Probiotics Improves IBS symptoms" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Bifidobacterium Probiotics and "Improves IBS symptoms". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Bifidobacterium Probiotics — randomized controlled trial

      Live PubMed search

      Live results for "Bifidobacterium Probiotics randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Bifidobacterium Probiotics and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Bifidobacterium Probiotics — meta-analysis

      Live PubMed search

      Live results for "Bifidobacterium Probiotics meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Bifidobacterium Probiotics and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Bifidobacterium Probiotics — pharmacokinetics

      Live PubMed search

      Live results for "Bifidobacterium Probiotics pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Bifidobacterium Probiotics and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Bifidobacterium Probiotics — safety adverse events

      Live PubMed search

      Live results for "Bifidobacterium Probiotics safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Bifidobacterium Probiotics and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Bifidobacterium Probiotics — dose response

      Live PubMed search

      Live results for "Bifidobacterium Probiotics dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Bifidobacterium Probiotics and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Bifidobacterium Probiotics — clinical evidence

      Live Scholar search

      Cross-database citation index for Bifidobacterium Probiotics as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.