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Supplements/Compound

Bifidobacterium longum 1714

Psychobiotic strain shown to reduce stress and improve memory.

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Overview

Psychobiotic strain shown to reduce stress and improve memory.

Natural sources
  • Endogenously produced or biosynthesized molecule
  • Standardized pharmaceutical- or food-grade supplement
  • Combined with cofactors that improve absorption or activity
Common forms
  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Forms & variants of Bifidobacterium Probiotics

Different chemical forms of Bifidobacterium Probiotics behave differently. Browse each form's mechanism, bioavailability, and best-use context.

Mechanism of action

Vagal afferent signaling modulates HPA axis and EEG patterns.

Pathways
  • · Vagal afferent signaling modulates HPA axis
  • · EEG patterns

Effects on the body

Decreases
perceived stress in healthy adults

Organ system effects

Brain & CNS

Bifidobacterium longum 1714 modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.

Evidence-based benefits

Reduces perceived stress in healthy adults

Moderate evidence

Potential side effects

Common
  • · Bifidobacterium longum 1714 is generally well-tolerated at evidence-based doses
  • · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
  • · Headache or transient fatigue reported by a small fraction of users
Rare
  • · Allergic or hypersensitivity reaction (rash, itching, swelling)
  • · Sleep disturbance if taken late in the day
Serious
  • · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing

Drug interactions

Prescription medications (general)
Always disclose Bifidobacterium longum 1714 use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
minor

Supplement interactions

Pairs well with
  • Omega-3 (EPA/DHA)
    Membrane fluidity and neuronal signaling support.
  • Alpha-GPC or CDP-choline
    Provides choline substrate for acetylcholine synthesis.
Avoid combining with

No specific avoidances listed.

Dosing & bioavailability

Typical dose
1 billion CFU
Best form
Most evidence is based on the capsule or softgel form.
Timing
Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
With food?
Either

Where to buy

Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

Scientific evidence8Show studies
RCTTransl Psychiatry · 2016

B. longum 1714 on stress and EEG

Allen AP, et al.

Crossover trial in 22 healthy men.

Key findings

Reduced cortisol awakening response and improved memory.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Bifidobacterium longum 1714 — Reduces perceived stress in healthy adults

Live PubMed search

Live results for "Bifidobacterium longum 1714 Reduces perceived stress in healthy adults" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "Reduces perceived stress in healthy adults". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Bifidobacterium longum 1714 — randomized controlled trial

Live PubMed search

Live results for "Bifidobacterium longum 1714 randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Bifidobacterium longum 1714 — meta-analysis

Live PubMed search

Live results for "Bifidobacterium longum 1714 meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Bifidobacterium longum 1714 — pharmacokinetics

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Live results for "Bifidobacterium longum 1714 pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Bifidobacterium longum 1714 — safety adverse events

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Live results for "Bifidobacterium longum 1714 safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewPubMed (NLM) · 1970

PubMed: Bifidobacterium longum 1714 — dose response

Live PubMed search

Live results for "Bifidobacterium longum 1714 dose response" across the PubMed/MEDLINE peer-reviewed index.

Key findings

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "dose response". Filter by RCT, meta-analysis, or year on the results page.

Open study
Systematic reviewGoogle Scholar · 1970

Google Scholar: Bifidobacterium longum 1714 — clinical evidence

Live Scholar search

Cross-database citation index for Bifidobacterium longum 1714 as it relates to "clinical evidence".

Key findings

Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

Open study
Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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