Overview
Psychobiotic strain shown to reduce stress and improve memory.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Forms & variants of Bifidobacterium Probiotics
Different chemical forms of Bifidobacterium Probiotics behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Vagal afferent signaling modulates HPA axis and EEG patterns.
- · Vagal afferent signaling modulates HPA axis
- · EEG patterns
Effects on the body
Organ system effects
Bifidobacterium longum 1714 modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.
Evidence-based benefits
Reduces perceived stress in healthy adults
Moderate evidencePotential side effects
- · Bifidobacterium longum 1714 is generally well-tolerated at evidence-based doses
- · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- · Headache or transient fatigue reported by a small fraction of users
- · Allergic or hypersensitivity reaction (rash, itching, swelling)
- · Sleep disturbance if taken late in the day
- · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Drug interactions
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
B. longum 1714 on stress and EEG
Allen AP, et al.
Crossover trial in 22 healthy men.
Reduced cortisol awakening response and improved memory.
PubMed: Bifidobacterium longum 1714 — Reduces perceived stress in healthy adults
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PubMed: Bifidobacterium longum 1714 — randomized controlled trial
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PubMed: Bifidobacterium longum 1714 — meta-analysis
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PubMed: Bifidobacterium longum 1714 — pharmacokinetics
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PubMed: Bifidobacterium longum 1714 — safety adverse events
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PubMed: Bifidobacterium longum 1714 — dose response
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Google Scholar: Bifidobacterium longum 1714 — clinical evidence
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