Supplement Scholar
Compound

Bifidobacterium longum 1714

Buy on Amazon ↗

Affiliate link: we may earn a commission at no extra cost to you. Disclosures

Bifidobacterium longum 1714. Psychobiotic strain shown to reduce stress and improve memory.

How it works. Vagal afferent signaling modulates HPA axis and EEG patterns.

What the research supports. 1 graded claims. Strongest: Reduces perceived stress in healthy adults (moderate).

How much to take. Typical dose: 1 billion CFU.

Side effects and interactions. 1 medication interaction listed. Serious: Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing.

Stacking. Pairs well with Omega-3 (EPA/DHA), Alpha-GPC or CDP-choline.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Bifidobacterium longum 1714. Anecdotes are not medical advice.

Bifidobacterium longum 1714. Psychobiotic strain shown to reduce stress and improve memory.

No single structure

What it is

Psychobiotic strain shown to reduce stress and improve memory.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Mood & AnxietyBrain & Cognitive

How it works

Vagal afferent signaling modulates HPA axis and EEG patterns.

Pathways

  • Vagal afferent signaling modulates HPA axis
  • EEG patterns

Effects

  • ↓perceived stress in healthy adults decreases

What the research supports

Reduces perceived stress in healthy adultsmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
1 billion CFU
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither
Best formMost evidence is based on the capsule or softgel form.
Shop Bifidobacterium longum 1714 on Amazon ↗

As an Amazon Associate I earn from qualifying purchases. Look for USP, NSF or Informed Sport seals before you buy.

Side effects & interactions

Common side effects

  • Bifidobacterium longum 1714 is generally well-tolerated at evidence-based doses
  • Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
  • Headache or transient fatigue reported by a small fraction of users

Serious

  • Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing

Medication interactions

Prescription medications (general)minor

Always disclose Bifidobacterium longum 1714 use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
  • Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Bifidobacterium longum 1714 — Reduces perceived stress in healthy adults ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "Reduces perceived stress in healthy adults". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Bifidobacterium longum 1714 — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Bifidobacterium longum 1714 — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Bifidobacterium longum 1714 and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

Loading discussion…