Metabolism Support

Resting metabolic rate.

Ranked by evidence strength across reported benefits.

AMPK activator with metformin-comparable glucose-lowering effects.

Chili pepper compound that mildly increases thermogenesis and reduces appetite.

Plant alkaloid that activates AMPK — metformin-like effects on glucose and lipids.

Shuttles long-chain fatty acids into mitochondria for β-oxidation.

Polyphenol-rich tea; EGCG modestly boosts metabolism and supports cardiovascular health.

Alpha-2 adrenergic antagonist used for fat loss and ED; significant cardiovascular risks.

Herb that blocks sweet taste perception and modestly lowers glucose.

Trace mineral marketed for blood sugar control and carbohydrate cravings.

Direct serotonin precursor with mood and sleep applications.

South American caffeine-containing tea with saponin and chlorogenic acid content.

Brown seaweed carotenoid studied for visceral fat reduction.

Hydroxycitric acid supplement marketed for weight loss; weak clinical evidence.