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evidence · mechanism · dose
Supplements/Compound

Zeaxanthin

Macular xanthophyll partner to lutein.

Eye Health

Overview

Macular xanthophyll partner to lutein.

Natural sources
    Common forms

      Mechanism of action

      Concentrates in central macula.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves visual performance

        Moderate evidence

        Potential side effects

        Common
        • · Well tolerated
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            2–4 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Zeaxanthin
            Amazon
            Wide selection · fast shipping
            Compound
            Zeaxanthin
            iHerb
            Global delivery · curated brands
            Compound
            Zeaxanthin
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Systematic reviewNutr Rev · 2007

            Zeaxanthin macular pigment

            Bone RA, et al.

            Mechanistic review

            Key findings

            Concentrates in central macula.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Zeaxanthin — Improves visual performance

            Live PubMed search

            Live results for "Zeaxanthin Improves visual performance" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Zeaxanthin and "Improves visual performance". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Zeaxanthin — randomized controlled trial

            Live PubMed search

            Live results for "Zeaxanthin randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Zeaxanthin and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Zeaxanthin — meta-analysis

            Live PubMed search

            Live results for "Zeaxanthin meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Zeaxanthin and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Zeaxanthin — pharmacokinetics

            Live PubMed search

            Live results for "Zeaxanthin pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Zeaxanthin and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Zeaxanthin — safety adverse events

            Live PubMed search

            Live results for "Zeaxanthin safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Zeaxanthin and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Zeaxanthin — dose response

            Live PubMed search

            Live results for "Zeaxanthin dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Zeaxanthin and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Zeaxanthin — clinical evidence

            Live Scholar search

            Cross-database citation index for Zeaxanthin as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.