Overview
Synergistic combo for calcium routing.
Mechanism of action
D3 increases calcium absorption; K2 directs to bone not arteries.
Effects on the body
Organ system effects
Evidence-based benefits
Better calcium handling
Moderate evidencePotential side effects
- · Bleeding with warfarin
Drug interactions
No notable interactions reported.
Supplement interactions
None listed.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.
Scientific evidence (8)
D3+K2 vs D3 alone
Kuang X, et al.
7 trials
D3+K2 had additive bone density benefit.
PubMed: Vitamin D3 + K2 — Better calcium handling
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PubMed: Vitamin D3 + K2 — randomized controlled trial
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PubMed: Vitamin D3 + K2 — meta-analysis
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PubMed: Vitamin D3 + K2 — pharmacokinetics
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PubMed: Vitamin D3 + K2 — safety adverse events
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PubMed: Vitamin D3 + K2 — dose response
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Google Scholar: Vitamin D3 + K2 — clinical evidence
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