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Tongkat Ali (Physta)

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Tongkat Ali (Physta). Water-extracted standardized tongkat ali for testosterone and stress.

How it works. Eurycomanone reduces SHBG-bound testosterone and lowers cortisol.

What the research supports. 1 graded claims. Strongest: Raises free testosterone in stressed adults (moderate).

How much to take. Typical dose: 200 mg Physta.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with A high-quality multivitamin, Omega-3 (EPA/DHA).

Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Tongkat Ali (Physta). Anecdotes are not medical advice.

Tongkat Ali (Physta). Water-extracted standardized tongkat ali for testosterone and stress.

Key compound: eurycomanoneC20H24O9 · 408.4 g/mol

What it is

Water-extracted standardized tongkat ali for testosterone and stress.

Food sources

Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice

Goals

How it works

Eurycomanone reduces SHBG-bound testosterone and lowers cortisol.

Pathways

  • Eurycomanone reduces SHBG-bound testosterone
  • lowers cortisol

Effects

  • ↑free testosterone in stressed adults increases

What the research supports

Raises free testosterone in stressed adultsmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
200 mg Physta
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodMorning
Best formMost evidence is based on the standardized extract capsule form.
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Side effects & interactions

Common side effects

  • Insomnia if taken late

Medication interactions

Prescription medications (general)minor

Always disclose Tongkat Ali (Physta) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
  • Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.

Common forms

  • Standardized extract capsule
  • Liquid tincture (alcohol or glycerin)
  • Powdered whole herb
  • Traditional decoction or tea

Key studies

8 studies cited in total.

PubMed: Tongkat Ali (Physta) — Raises free testosterone in stressed adults ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Tongkat Ali (Physta) and "Raises free testosterone in stressed adults". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Tongkat Ali (Physta) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Tongkat Ali (Physta) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Tongkat Ali (Physta) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Tongkat Ali (Physta) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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