Overview
GHRH analog approved for HIV-associated visceral adiposity.
- Synthetic peptide manufactured to pharmaceutical or research-grade purity
- Subcutaneous injection, sublingual, or oral preparation depending on bioavailability
- Compounded by a licensed pharmacy for clinical use
- Subcutaneous injection
- Oral or sublingual lozenge
- Nasal spray
- Compounded topical
Mechanism of action
Stimulates endogenous GH release via pituitary GHRH receptor.
- · Stimulates endogenous GH release via pituitary GHRH receptor
Effects on the body
Organ system effects
Evidence-based benefits
Reduces visceral adipose tissue
Strong evidencePotential side effects
- · Injection site reactions
- · Hyperglycemia
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
- ·Most research peptides are not FDA-approved for human use outside investigational protocols.
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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CapsulesPre-measured Tesamorelin (Ref) capsules — easiest for travel and consistent daily dosing without scoops or scales.Tesamorelin (Ref) capsules
PowderBulk unflavored Tesamorelin (Ref) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Tesamorelin (Ref) powder unflavored
Best sellersMost-purchased Tesamorelin (Ref) products on Amazon — a quick way to see what's reviewed widely before you commit.Tesamorelin (Ref) best sellerScientific evidence8Show studiesHide studies
Tesamorelin in HIV lipodystrophy
Falutz J, et al.
26-week DB-RCT in 412 HIV patients.
Reduced VAT by ~15% vs placebo.
PubMed: Tesamorelin (Ref) — Reduces visceral adipose tissue
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