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SUPPLEMENT_SCHOLAR
evidence · mechanism · dose
Supplements/Mineral

Strontium Citrate

Mineral that substitutes for calcium in bone — controversial but increases BMD measurements.

Bone DensityOsteoporosis PreventionBone Health

Overview

Mineral that substitutes for calcium in bone — controversial but increases BMD measurements.

Natural sources
    Common forms

      Mechanism of action

      Replaces Ca²⁺ in hydroxyapatite, stimulating osteoblasts and inhibiting osteoclasts.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Increases BMD (strontium ranelate Rx — CV risk)

        Moderate evidence

        Potential side effects

        Common
          Rare
          • · GI upset
          Serious
          • · CV/VTE risk (ranelate Rx)

          Drug interactions

          Calcium supplements
          Compete for absorption — separate by 2h.
          moderate

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          340–680 mg elemental Sr (citrate form)
          With food?
          Empty stomach away from calcium

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Mineral
          Strontium Ci…
          Amazon
          Wide selection · fast shipping
          Mineral
          Strontium Ci…
          iHerb
          Global delivery · curated brands
          Mineral
          Strontium Ci…
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (8)

          Systematic reviewOsteoporos Int · 2014

          Strontium citrate for bone density

          Reginster JY, et al.

          Review of strontium salts in osteoporosis.

          Key findings

          Improved BMD; cardiovascular caution with strontium ranelate.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Strontium Citrate — Increases BMD

          Live PubMed search

          Live results for "Strontium Citrate Increases BMD" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Strontium Citrate and "Increases BMD". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Strontium Citrate — randomized controlled trial

          Live PubMed search

          Live results for "Strontium Citrate randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Strontium Citrate and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Strontium Citrate — meta-analysis

          Live PubMed search

          Live results for "Strontium Citrate meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Strontium Citrate and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Strontium Citrate — pharmacokinetics

          Live PubMed search

          Live results for "Strontium Citrate pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Strontium Citrate and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Strontium Citrate — safety adverse events

          Live PubMed search

          Live results for "Strontium Citrate safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Strontium Citrate and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Strontium Citrate — dose response

          Live PubMed search

          Live results for "Strontium Citrate dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Strontium Citrate and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Strontium Citrate — clinical evidence

          Live Scholar search

          Cross-database citation index for Strontium Citrate as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.