Overview
Mineral that substitutes for calcium in bone — controversial but increases BMD measurements.
- Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
- Fortified foods such as cereals, breads, plant milks, and table salt
- Mineral supplements as chelates, citrates, glycinates, or inorganic salts
- Chelated form (glycinate, bisglycinate, citrate, malate)
- Inorganic salt (oxide, sulfate, chloride)
- Liquid ionic solution
- Topical or transdermal preparation
Mechanism of action
Replaces Ca²⁺ in hydroxyapatite, stimulating osteoblasts and inhibiting osteoclasts.
- · Replaces Ca²⁺ in hydroxyapatite, stimulating osteoblasts
- · inhibiting osteoclasts
Effects on the body
Organ system effects
Strontium Citrate contributes to bone mineralization, osteoblast activity, or calcium-phosphate homeostasis.
Evidence-based benefits
Increases BMD (strontium ranelate Rx — CV risk)
Moderate evidencePotential side effects
- · GI upset
- · CV/VTE risk (ranelate Rx)
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Strontium citrate for bone density
Reginster JY, et al.
Review of strontium salts in osteoporosis.
Improved BMD; cardiovascular caution with strontium ranelate.
PubMed: Strontium Citrate — Increases BMD
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PubMed: Strontium Citrate — randomized controlled trial
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PubMed: Strontium Citrate — dose response
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