Overview
Enteric-coated proteolytic enzyme for inflammation and mucus.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Forms & variants of Serrapeptase
Different chemical forms of Serrapeptase behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Hydrolyzes bradykinin, fibrin, and inflammatory mediators.
- · Hydrolyzes bradykinin, fibrin
- · and inflammatory mediators
Effects on the body
Organ system effects
Evidence-based benefits
Reduces post-surgical swelling
Moderate evidencePotential side effects
- · GI upset
- · Pneumonitis
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Serrapeptase post dental surgery
Tachibana M, et al.
RCT in 174 patients after molar extraction.
Significantly reduced swelling and trismus vs placebo.
PubMed: Serrapeptase (Extra) — Reduces post-surgical swelling
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PubMed: Serrapeptase (Extra) — randomized controlled trial
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PubMed: Serrapeptase (Extra) — meta-analysis
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PubMed: Serrapeptase (Extra) — pharmacokinetics
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PubMed: Serrapeptase (Extra) — safety adverse events
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PubMed: Serrapeptase (Extra) — dose response
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Google Scholar: Serrapeptase (Extra) — clinical evidence
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Cross-database citation index for Serrapeptase (Extra) as it relates to "clinical evidence".
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