Overview
Adaptogen for stress-related fatigue and burnout.
- Whole dried plant material (root, leaf, flower, or aerial parts depending on the species)
- Standardized hydroethanolic or aqueous extract (capsule, tincture, or tea)
- Powdered traditional preparation used in Ayurvedic, TCM, or Western herbal practice
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Forms & variants of Rhodiola Rosea
Different chemical forms of Rhodiola Rosea behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Rosavin/salidroside modulate HPA axis and monoamine reuptake.
- · Rosavin/salidroside modulate HPA axis
- · monoamine reuptake
Effects on the body
Organ system effects
Rhodiola SHR-5 (Fatigue) supports mitochondrial ATP production and fatigue resistance.
Rhodiola SHR-5 (Fatigue) acts on central nervous system targets implicated in attention, memory, and neuroprotection.
Evidence-based benefits
Reduces fatigue scores in burnout
Moderate evidencePotential side effects
- · Insomnia if late
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Rhodiola SHR-5 (Fatigue) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Rhodiola SHR-5 (Fatigue) third party tested NSF
CapsulesPre-measured Rhodiola SHR-5 (Fatigue) capsules — easiest for travel and consistent daily dosing without scoops or scales.Rhodiola SHR-5 (Fatigue) capsules
PowderBulk unflavored Rhodiola SHR-5 (Fatigue) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Rhodiola SHR-5 (Fatigue) powder unflavored
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Rhodiola in burnout
Olsson EM, et al.
28-day DB-RCT in 60 burnout patients.
Reduced fatigue and improved cognitive performance vs placebo.
PubMed: Rhodiola SHR-5 (Fatigue) — Reduces fatigue scores in burnout
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PubMed: Rhodiola SHR-5 (Fatigue) — randomized controlled trial
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PubMed: Rhodiola SHR-5 (Fatigue) — meta-analysis
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PubMed: Rhodiola SHR-5 (Fatigue) — dose response
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Google Scholar: Rhodiola SHR-5 (Fatigue) — clinical evidence
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