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evidence · mechanism · dose
Supplements/Compound

Quercetin + Dasatinib (D+Q)

Reference senolytic combination cycled to clear senescent cells.

Healthy Aging

Overview

Reference senolytic combination cycled to clear senescent cells.

Natural sources
    Common forms

      Forms & variants of Quercetin

      Different chemical forms of Quercetin behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Quercetin

      Flavonoid with antihistamine and senolytic effects; pairs with bromelain or vitamin C.

      Parent
      Quercetin

      Flavonoid with antihistamine, anti-viral, and senolytic activity.

      Mechanism of action

      Inhibits anti-apoptotic Bcl-XL and SRC family kinases in senescent cells.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Improves physical function in IPF (open-label)

        Limited evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious
          • · Use only with medical oversight

          Drug interactions

          QT-prolonging drugs
          Dasatinib lengthens QT interval.
          severe

          Supplement interactions

          Pairs well with

          None listed.

          Avoid combining with

          No specific avoidances listed.

          Dosing & bioavailability

          Typical dose
          Research protocols only

          Where to buy

          Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

          Compound
          Quercetin + …
          Amazon
          Wide selection · fast shipping
          Compound
          Quercetin + …
          iHerb
          Global delivery · curated brands
          Compound
          Quercetin + …
          Thorne
          Practitioner-grade · NSF tested

          Scientific evidence (8)

          CohortEBioMedicine · 2019

          Dasatinib + quercetin in IPF

          Justice JN, et al.

          Open-label trial in 14 IPF patients.

          Key findings

          Improved 6-min walk distance and gait speed.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Quercetin + Dasatinib (D+Q) — Improves physical function in IPF

          Live PubMed search

          Live results for "Quercetin + Dasatinib (D+Q) Improves physical function in IPF" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "Improves physical function in IPF". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Quercetin + Dasatinib (D+Q) — randomized controlled trial

          Live PubMed search

          Live results for "Quercetin + Dasatinib (D+Q) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Quercetin + Dasatinib (D+Q) — meta-analysis

          Live PubMed search

          Live results for "Quercetin + Dasatinib (D+Q) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Quercetin + Dasatinib (D+Q) — pharmacokinetics

          Live PubMed search

          Live results for "Quercetin + Dasatinib (D+Q) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Quercetin + Dasatinib (D+Q) — safety adverse events

          Live PubMed search

          Live results for "Quercetin + Dasatinib (D+Q) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewPubMed (NLM) · 1970

          PubMed: Quercetin + Dasatinib (D+Q) — dose response

          Live PubMed search

          Live results for "Quercetin + Dasatinib (D+Q) dose response" across the PubMed/MEDLINE peer-reviewed index.

          Key findings

          Opens current human and preclinical literature matching Quercetin + Dasatinib (D+Q) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

          Open study
          Systematic reviewGoogle Scholar · 1970

          Google Scholar: Quercetin + Dasatinib (D+Q) — clinical evidence

          Live Scholar search

          Cross-database citation index for Quercetin + Dasatinib (D+Q) as it relates to "clinical evidence".

          Key findings

          Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

          Open study
          Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.