Overview
Reference senolytic combination cycled to clear senescent cells.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Forms & variants of Quercetin
Different chemical forms of Quercetin behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Inhibits anti-apoptotic Bcl-XL and SRC family kinases in senescent cells.
- · Inhibits anti-apoptotic Bcl-XL
- · SRC family kinases in senescent cells
Effects on the body
Organ system effects
Quercetin + Dasatinib (D+Q) acts on hallmarks of aging including oxidative stress, mitochondrial dysfunction, and senescence signaling.
Evidence-based benefits
Improves physical function in IPF (open-label)
Limited evidencePotential side effects
- · GI upset
- · Use only with medical oversight
Drug interactions
Supplement interactions
- NAD+ precursor (NMN or NR)Complementary mitochondrial and sirtuin support.
- Omega-3Lowers inflammation and supports membrane integrity.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Dasatinib + quercetin in IPF
Justice JN, et al.
Open-label trial in 14 IPF patients.
Improved 6-min walk distance and gait speed.
PubMed: Quercetin + Dasatinib (D+Q) — Improves physical function in IPF
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PubMed: Quercetin + Dasatinib (D+Q) — randomized controlled trial
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PubMed: Quercetin + Dasatinib (D+Q) — meta-analysis
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PubMed: Quercetin + Dasatinib (D+Q) — pharmacokinetics
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PubMed: Quercetin + Dasatinib (D+Q) — dose response
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Google Scholar: Quercetin + Dasatinib (D+Q) — clinical evidence
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