Overview
Flavonoid with antihistamine and senolytic effects; pairs with bromelain or vitamin C.
- Onions
- Apples
- Capers
- Quercetin dihydrate
- Quercetin phytosome
Forms & variants of Quercetin
Different chemical forms of Quercetin behave differently. Browse each form's mechanism, bioavailability, and best-use context.
Mechanism of action
Inhibits mast cell degranulation; senolytic with dasatinib in animals.
- · Mast cell stabilization
- · Senolysis
Effects on the body
Organ system effects
Quercetin modulates innate and adaptive immune responses, including cytokine signaling and barrier function.
Quercetin acts on hallmarks of aging including oxidative stress, mitochondrial dysfunction, and senescence signaling.
Evidence-based benefits
Reduces allergic rhinitis symptoms
Limited evidenceReduces URI incidence in athletes
Moderate evidencePotential side effects
- · Headache
- · Nausea
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Autoimmune disease (theoretical immune activation)
- ·Immunosuppressants
Supplement interactions
- BromelainBoosts quercetin absorption.
- ZincQuercetin acts as zinc ionophore.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence9Show studiesHide studies
Quercetin and blood pressure: a meta-analysis
Serban MC, et al.
Meta-analysis of quercetin RCTs.
Significant reductions in systolic and diastolic BP.
PubMed: Quercetin — Reduces allergic rhinitis symptoms
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PubMed: Quercetin — Reduces URI incidence in athletes
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PubMed: Quercetin — randomized controlled trial
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PubMed: Quercetin — meta-analysis
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PubMed: Quercetin — pharmacokinetics
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PubMed: Quercetin — safety adverse events
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PubMed: Quercetin — dose response
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Google Scholar: Quercetin — clinical evidence
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Cross-database citation index for Quercetin as it relates to "clinical evidence".
Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.