SYS ONLINE
SUPPLEMENT_SCHOLAR
evidence · mechanism · dose
Supplements/Compound

Pterostilbene

Bioavailable resveratrol analog with longer half-life.

Healthy AgingCardiovascular Health

Overview

Bioavailable resveratrol analog with longer half-life.

Natural sources
  • Blueberries
  • Grapes
Common forms
  • Pterostilbene capsule

Forms & variants of Pterostilbene

Different chemical forms of Pterostilbene behave differently. Browse each form's mechanism, bioavailability, and best-use context.

High-bio
Pterostilbene (Extra)

Methylated resveratrol analog with superior bioavailability.

Mechanism of action

Similar to resveratrol but better bioavailability and SIRT1 activation.

Pathways
  • · SIRT1 activation

Effects on the body

Supports
Lipid profile

Organ system effects

Evidence-based benefits

May raise LDL at higher doses (paradox)

Limited evidence

Potential side effects

Common
    Rare
      Serious

        Drug interactions

        No notable interactions reported.

        Supplement interactions

        Pairs well with

        None listed.

        Avoid combining with

        No specific avoidances listed.

        Dosing & bioavailability

        Typical dose
        50–250 mg/d

        Where to buy

        Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

        Compound
        Pterostilbene
        Amazon
        Wide selection · fast shipping
        Compound
        Pterostilbene
        iHerb
        Global delivery · curated brands
        Compound
        Pterostilbene
        Thorne
        Practitioner-grade · NSF tested

        Scientific evidence (8)

        RCTJ Diet Suppl · 2014

        Pterostilbene on cholesterol and blood pressure

        Riche DM, et al.

        6-8 week RCT of pterostilbene 250 mg/d.

        Key findings

        Reduced BP; modest LDL increase at higher doses.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Pterostilbene — May raise LDL at higher doses

        Live PubMed search

        Live results for "Pterostilbene May raise LDL at higher doses" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Pterostilbene and "May raise LDL at higher doses". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Pterostilbene — randomized controlled trial

        Live PubMed search

        Live results for "Pterostilbene randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Pterostilbene and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Pterostilbene — meta-analysis

        Live PubMed search

        Live results for "Pterostilbene meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Pterostilbene and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Pterostilbene — pharmacokinetics

        Live PubMed search

        Live results for "Pterostilbene pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Pterostilbene and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Pterostilbene — safety adverse events

        Live PubMed search

        Live results for "Pterostilbene safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Pterostilbene and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewPubMed (NLM) · 1970

        PubMed: Pterostilbene — dose response

        Live PubMed search

        Live results for "Pterostilbene dose response" across the PubMed/MEDLINE peer-reviewed index.

        Key findings

        Opens current human and preclinical literature matching Pterostilbene and "dose response". Filter by RCT, meta-analysis, or year on the results page.

        Open study
        Systematic reviewGoogle Scholar · 1970

        Google Scholar: Pterostilbene — clinical evidence

        Live Scholar search

        Cross-database citation index for Pterostilbene as it relates to "clinical evidence".

        Key findings

        Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

        Open study
        Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.