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evidence · mechanism · dose
Supplements/Herb

Oil of Oregano

Carvacrol-rich essential oil with broad antimicrobial activity (in vitro).

Infection SupportImmune Function (alias)Gut Health

Overview

Carvacrol-rich essential oil with broad antimicrobial activity (in vitro).

Natural sources
    Common forms

      Mechanism of action

      Carvacrol disrupts microbial membranes.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        In vitro antimicrobial

        Limited evidence

        Potential side effects

        Common
        • · Heartburn
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            50–100 mg standardized to 70%+ carvacrol
            With food?
            With food

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
            Oil of Oregano
            Amazon
            Wide selection · fast shipping
            Herb
            Oil of Oregano
            iHerb
            Global delivery · curated brands
            Herb
            Oil of Oregano
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Systematic reviewMolecules · 2017

            Origanum vulgare essential oil and antimicrobial activity

            Leyva-López N, et al.

            Review of oregano oil's antimicrobial activity.

            Key findings

            Broad-spectrum activity in vitro; limited clinical trials.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Oil of Oregano — In vitro antimicrobial

            Live PubMed search

            Live results for "Oil of Oregano In vitro antimicrobial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Oil of Oregano and "In vitro antimicrobial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Oil of Oregano — randomized controlled trial

            Live PubMed search

            Live results for "Oil of Oregano randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Oil of Oregano and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Oil of Oregano — meta-analysis

            Live PubMed search

            Live results for "Oil of Oregano meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Oil of Oregano and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Oil of Oregano — pharmacokinetics

            Live PubMed search

            Live results for "Oil of Oregano pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Oil of Oregano and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Oil of Oregano — safety adverse events

            Live PubMed search

            Live results for "Oil of Oregano safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Oil of Oregano and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Oil of Oregano — dose response

            Live PubMed search

            Live results for "Oil of Oregano dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Oil of Oregano and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Oil of Oregano — clinical evidence

            Live Scholar search

            Cross-database citation index for Oil of Oregano as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.