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evidence · mechanism · dose
Supplements/Herb

Kudzu (Pueraria lobata)

Isoflavone-rich root that reduces alcohol intake.

Liver Health

Overview

Isoflavone-rich root that reduces alcohol intake.

Natural sources
    Common forms

      Forms & variants of Kudzu (Pueraria lobata)

      Different chemical forms of Kudzu (Pueraria lobata) behave differently. Browse each form's mechanism, bioavailability, and best-use context.

      Parent
      Kudzu (Pueraria lobata)

      Isoflavone-rich root — reduces alcohol craving and intake in human trials.

      Mechanism of action

      Puerarin/daidzin inhibit ALDH-2 and modulate cortical reward circuits.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Reduces ad-lib alcohol consumption acutely

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Safety & non-supplemental interactions

            Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

            Avoid if you are
            • ·Pregnant or breastfeeding (insufficient safety data)
            • ·Children under 18 (unless directed by a clinician)

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            250–500 mg extract
            With food?
            Before drinking

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Herb
            Kudzu (Puera…
            Amazon
            Wide selection · fast shipping
            Herb
            Kudzu (Puera…
            iHerb
            Global delivery · curated brands
            Herb
            Kudzu (Puera…
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTAlcohol Clin Exp Res · 2005

            Kudzu reduces alcohol intake

            Lukas SE, et al.

            Naturalistic drinking laboratory study in 14 adults.

            Key findings

            Significantly reduced beer consumption vs placebo.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Kudzu (Pueraria lobata) — Reduces ad-lib alcohol consumption acutely

            Live PubMed search

            Live results for "Kudzu (Pueraria lobata) Reduces ad-lib alcohol consumption acutely" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Kudzu (Pueraria lobata) and "Reduces ad-lib alcohol consumption acutely". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Kudzu (Pueraria lobata) — randomized controlled trial

            Live PubMed search

            Live results for "Kudzu (Pueraria lobata) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Kudzu (Pueraria lobata) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Kudzu (Pueraria lobata) — meta-analysis

            Live PubMed search

            Live results for "Kudzu (Pueraria lobata) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Kudzu (Pueraria lobata) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Kudzu (Pueraria lobata) — pharmacokinetics

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            Live results for "Kudzu (Pueraria lobata) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Kudzu (Pueraria lobata) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Kudzu (Pueraria lobata) — safety adverse events

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            Live results for "Kudzu (Pueraria lobata) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

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            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Kudzu (Pueraria lobata) — dose response

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            Live results for "Kudzu (Pueraria lobata) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Kudzu (Pueraria lobata) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Kudzu (Pueraria lobata) — clinical evidence

            Live Scholar search

            Cross-database citation index for Kudzu (Pueraria lobata) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.