Overview
High-DHA for brain health.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Major structural lipid in brain and retina.
- · Major structural lipid in brain
Effects on the body
Organ system effects
DHA-Dominant Fish Oil acts on central nervous system targets implicated in attention, memory, and neuroprotection.
DHA-Dominant Fish Oil concentrates in ocular tissues (macula, retina, lens) where it contributes to photoprotection or antioxidant defense.
Evidence-based benefits
Cognitive support
Moderate evidencePotential side effects
- · GI upset
Drug interactions
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
DHA for cognition
Yurko-Mauro K, et al.
485 older adults
Improved memory.
PubMed: DHA-Dominant Fish Oil — Cognitive support
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PubMed: DHA-Dominant Fish Oil — randomized controlled trial
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PubMed: DHA-Dominant Fish Oil — meta-analysis
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PubMed: DHA-Dominant Fish Oil — pharmacokinetics
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PubMed: DHA-Dominant Fish Oil — dose response
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Google Scholar: DHA-Dominant Fish Oil — clinical evidence
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