Overview
Licorice with glycyrrhizin removed; soothes GI mucosa without BP effect.
- Glycyrrhiza glabra (processed)
- Chewable DGL tablets
Mechanism of action
Increases mucin secretion and epidermal growth factor in gastric mucosa.
- · Mucin secretion ↑
Effects on the body
Organ system effects
Heals NSAID gastritis and aphthous ulcers.
Evidence-based benefits
Heals gastric ulcers and reduces NSAID gastritis
Moderate evidencePotential side effects
- · DGL (Deglycyrrhizinated Licorice) is generally well-tolerated at evidence-based doses
- · Mild GI discomfort (nausea, loose stools, or bloating) possible at higher intakes
- · Headache or transient fatigue reported by a small fraction of users
- · Allergic or hypersensitivity reaction (rash, itching, swelling)
- · Sleep disturbance if taken late in the day
- · Discontinue and seek medical advice if symptoms are severe, persistent, or include difficulty breathing
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified DGL (Deglycyrrhizinated Licorice) — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.DGL (Deglycyrrhizinated Licorice) third party tested NSF
CapsulesPre-measured DGL (Deglycyrrhizinated Licorice) capsules — easiest for travel and consistent daily dosing without scoops or scales.DGL (Deglycyrrhizinated Licorice) capsules
PowderBulk unflavored DGL (Deglycyrrhizinated Licorice) powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.DGL (Deglycyrrhizinated Licorice) powder unflavored
Best sellersMost-purchased DGL (Deglycyrrhizinated Licorice) products on Amazon — a quick way to see what's reviewed widely before you commit.DGL (Deglycyrrhizinated Licorice) best sellerScientific evidence8Show studiesHide studies
DGL for functional dyspepsia
Raveendra KR, et al.
30-day RCT of DGL 150 mg twice daily.
Significant symptom improvement vs placebo.
PubMed: DGL (Deglycyrrhizinated Licorice) — Heals gastric ulcers and reduces NSAID gastritis
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