SYS ONLINE
Supplements/Compound

Chlorella

Green algae with chlorophyll.

Buy

Overview

Green algae with chlorophyll.

Natural sources
  • Endogenously produced or biosynthesized molecule
  • Standardized pharmaceutical- or food-grade supplement
  • Combined with cofactors that improve absorption or activity
Common forms
  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Mechanism of action

Binds heavy metals; CGF growth factor.

Pathways
  • · Binds heavy metals
  • · CGF growth factor

Effects on the body

Supports
Heavy metal chelation

Organ system effects

Immune System

Chlorella modulates innate and adaptive immune responses, including cytokine signaling and barrier function.

Evidence-based benefits

Heavy metal chelation

Moderate evidence

Potential side effects

Common
  • · GI upset
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Chlorella use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Safety & non-supplemental interactions

      Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.

      Avoid with these conditions
      • ·Autoimmune disease (theoretical immune activation)
      Avoid / monitor with these medications
      • ·Immunosuppressants

      Supplement interactions

      Pairs well with
      • Vitamin D3 + K2
        Foundational immune modulation.
      • Zinc
        Required cofactor for innate and adaptive immune function.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      2–6 g
      Best form
      Most evidence is based on the capsule or softgel form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      With a meal containing fat for fat-soluble compounds; otherwise either.

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence8Show studies
      RCTJ Med Food · 2005

      Chlorella for dioxin

      Nakano S, et al.

      Pregnant women

      Key findings

      Reduced dioxin transfer to milk.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Chlorella — Heavy metal chelation

      Live PubMed search

      Live results for "Chlorella Heavy metal chelation" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Chlorella and "Heavy metal chelation". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Chlorella — randomized controlled trial

      Live PubMed search

      Live results for "Chlorella randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Chlorella and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Chlorella — meta-analysis

      Live PubMed search

      Live results for "Chlorella meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Chlorella and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Chlorella — pharmacokinetics

      Live PubMed search

      Live results for "Chlorella pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Chlorella and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Chlorella — safety adverse events

      Live PubMed search

      Live results for "Chlorella safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Chlorella and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Chlorella — dose response

      Live PubMed search

      Live results for "Chlorella dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Chlorella and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Chlorella — clinical evidence

      Live Scholar search

      Cross-database citation index for Chlorella as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

      Community discussion

      (0 threads)

      Share your experience or read what others have tried. Anecdotes are not medical advice.

      Sign in or create a free account to post or reply.
      Loading discussion…