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evidence · mechanism · dose
Supplements/Vitamin

Allithiamine

Garlic-derived fat-soluble thiamine.

Energy ProductionBrain & Cognitive

Overview

Garlic-derived fat-soluble thiamine.

Natural sources
    Common forms

      Mechanism of action

      Disulfide derivative crosses cell membranes.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Better than HCl thiamine

        Moderate evidence

        Potential side effects

        Common
        • · Garlic odor
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            50–100 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

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            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            Systematic reviewEvid Based Complement Alternat Med · 2006

            Allithiamine bioavailability

            Lonsdale D

            Pharmacological review

            Key findings

            Higher tissue uptake than thiamine HCl.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Allithiamine — Better than HCl thiamine

            Live PubMed search

            Live results for "Allithiamine Better than HCl thiamine" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Allithiamine and "Better than HCl thiamine". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Allithiamine — randomized controlled trial

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            Live results for "Allithiamine randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Allithiamine and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Allithiamine — meta-analysis

            Live PubMed search

            Live results for "Allithiamine meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Allithiamine and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Allithiamine — pharmacokinetics

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            Live results for "Allithiamine pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Allithiamine and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Allithiamine — safety adverse events

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            Live results for "Allithiamine safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Allithiamine and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Allithiamine — dose response

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            Live results for "Allithiamine dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Allithiamine and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Allithiamine — clinical evidence

            Live Scholar search

            Cross-database citation index for Allithiamine as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.