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Supplements/Mineral

Zinc-L-Carnosine

Zinc-carnosine complex for GI lining.

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Overview

Zinc-carnosine complex for GI lining.

Natural sources
  • Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)
  • Fortified foods such as cereals, breads, plant milks, and table salt
  • Mineral supplements as chelates, citrates, glycinates, or inorganic salts
Common forms
  • Chelated form (glycinate, bisglycinate, citrate, malate)
  • Inorganic salt (oxide, sulfate, chloride)
  • Liquid ionic solution
  • Topical or transdermal preparation

Mechanism of action

Adheres to ulcer base; antioxidant.

Pathways
  • · Adheres to ulcer base
  • · antioxidant

Effects on the body

Supports
Heals gastric ulcers

Organ system effects

Digestive / Gut

Zinc-L-Carnosine influences gut motility, mucosal integrity, or microbial balance in the GI tract.

Evidence-based benefits

Heals gastric ulcers

Moderate evidence

Potential side effects

Common
  • · Well tolerated
Rare
    Serious

      Drug interactions

      Prescription medications (general)
      Always disclose Zinc-L-Carnosine use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
      minor

      Supplement interactions

      Pairs well with
      • Multi-strain probiotic
        Supports microbiome diversity and barrier integrity.
      • L-glutamine
        Substrate for enterocyte energy and tight-junction maintenance.
      Avoid combining with

      No specific avoidances listed.

      Dosing & bioavailability

      Typical dose
      150 mg BID
      Best form
      Most evidence is based on the chelated form (glycinate, bisglycinate, citrate, malate) form.
      Timing
      Consistent daily timing recommended; split larger doses if GI tolerance is a concern.
      With food?
      Either with or without food.

      Where to buy

      Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.

      Scientific evidence8Show studies
      AnimalJ Pharmacol Exp Ther · 1998

      Polaprezinc for ulcers

      Ito M, et al.

      Ulcer model

      Key findings

      Accelerated ulcer healing.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Zinc-L-Carnosine — Heals gastric ulcers

      Live PubMed search

      Live results for "Zinc-L-Carnosine Heals gastric ulcers" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Zinc-L-Carnosine and "Heals gastric ulcers". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Zinc-L-Carnosine — randomized controlled trial

      Live PubMed search

      Live results for "Zinc-L-Carnosine randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Zinc-L-Carnosine and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Zinc-L-Carnosine — meta-analysis

      Live PubMed search

      Live results for "Zinc-L-Carnosine meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Zinc-L-Carnosine and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Zinc-L-Carnosine — pharmacokinetics

      Live PubMed search

      Live results for "Zinc-L-Carnosine pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Zinc-L-Carnosine and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Zinc-L-Carnosine — safety adverse events

      Live PubMed search

      Live results for "Zinc-L-Carnosine safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Zinc-L-Carnosine and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewPubMed (NLM) · 1970

      PubMed: Zinc-L-Carnosine — dose response

      Live PubMed search

      Live results for "Zinc-L-Carnosine dose response" across the PubMed/MEDLINE peer-reviewed index.

      Key findings

      Opens current human and preclinical literature matching Zinc-L-Carnosine and "dose response". Filter by RCT, meta-analysis, or year on the results page.

      Open study
      Systematic reviewGoogle Scholar · 1970

      Google Scholar: Zinc-L-Carnosine — clinical evidence

      Live Scholar search

      Cross-database citation index for Zinc-L-Carnosine as it relates to "clinical evidence".

      Key findings

      Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

      Open study
      Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.

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