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Mineral

Polaprezinc

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Polaprezinc. Japanese ulcer treatment.

How it works. Zinc-carnosine chelate adheres to ulcers.

What the research supports. 1 graded claims. Strongest: Heals gastric ulcers (moderate).

How much to take. Typical dose: 75 mg BID.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Multi-strain probiotic, L-glutamine.

Common forms. Available as Chelated form (glycinate, bisglycinate, citrate, malate), Inorganic salt (oxide, sulfate, chloride), Liquid ionic solution, Topical or transdermal preparation.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Polaprezinc. Anecdotes are not medical advice.

Polaprezinc. Japanese ulcer treatment.

Molecular structureC9H12N4O3Zn · 289.6 g/mol

What it is

Japanese ulcer treatment.

Food sources

Whole foods (leafy greens, legumes, nuts, seeds, seafood, animal proteins)Fortified foods such as cereals, breads, plant milks, and table saltMineral supplements as chelates, citrates, glycinates, or inorganic salts

How it works

Zinc-carnosine chelate adheres to ulcers.

Pathways

  • Zinc-carnosine chelate adheres to ulcers

Effects

  • +Heals gastric ulcers supports

What the research supports

Heals gastric ulcersmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
75 mg BID
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodEither with or without food.
Best formMost evidence is based on the chelated form (glycinate, bisglycinate, citrate, malate) form.
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Side effects & interactions

Common side effects

  • Metallic taste

Medication interactions

Prescription medications (general)minor

Always disclose Polaprezinc use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

Common forms

  • Chelated form (glycinate, bisglycinate, citrate, malate)
  • Inorganic salt (oxide, sulfate, chloride)
  • Liquid ionic solution
  • Topical or transdermal preparation

Key studies

8 studies cited in total.

PubMed: Polaprezinc — Heals gastric ulcers ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Polaprezinc and "Heals gastric ulcers". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Polaprezinc — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Polaprezinc and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Polaprezinc — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Polaprezinc and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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