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evidence · mechanism · dose
Supplements/Mineral

Vanadyl Sulfate

Insulin-mimetic trace element.

Overview

Insulin-mimetic trace element.

Natural sources
    Common forms

      Mechanism of action

      Inhibits PTP1B; insulin receptor potentiation.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        May improve insulin sensitivity

        Moderate evidence

        Potential side effects

        Common
        • · GI upset
        • · Renal concerns
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            7.5–100 mg

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Mineral
            Vanadyl Sulf…
            Amazon
            Wide selection · fast shipping
            Mineral
            Vanadyl Sulf…
            iHerb
            Global delivery · curated brands
            Mineral
            Vanadyl Sulf…
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTJ Clin Endocrinol Metab · 2001

            Vanadyl in T2DM

            Cusi K, et al.

            11 T2DM

            Key findings

            Improved hepatic and peripheral insulin sensitivity.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Vanadyl Sulfate — May improve insulin sensitivity

            Live PubMed search

            Live results for "Vanadyl Sulfate May improve insulin sensitivity" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Vanadyl Sulfate and "May improve insulin sensitivity". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Vanadyl Sulfate — randomized controlled trial

            Live PubMed search

            Live results for "Vanadyl Sulfate randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Vanadyl Sulfate and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Vanadyl Sulfate — meta-analysis

            Live PubMed search

            Live results for "Vanadyl Sulfate meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Vanadyl Sulfate and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Vanadyl Sulfate — pharmacokinetics

            Live PubMed search

            Live results for "Vanadyl Sulfate pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Vanadyl Sulfate and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Vanadyl Sulfate — safety adverse events

            Live PubMed search

            Live results for "Vanadyl Sulfate safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Vanadyl Sulfate and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Vanadyl Sulfate — dose response

            Live PubMed search

            Live results for "Vanadyl Sulfate dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Vanadyl Sulfate and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Vanadyl Sulfate — clinical evidence

            Live Scholar search

            Cross-database citation index for Vanadyl Sulfate as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.