Overview
Pyrimidine that supports synaptic membrane synthesis.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Combines with choline and omega-3 to form phosphatidylcholine in synapses.
- · Combines with choline
- · omega-3 to form phosphatidylcholine in synapses
Effects on the body
Organ system effects
Uridine Monophosphate acts on central nervous system targets implicated in attention, memory, and neuroprotection.
Evidence-based benefits
Improves cognition in MCI when stacked with omega-3 + choline
Moderate evidencePotential side effects
- · Headache
Drug interactions
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Third-party testedIndependently verified Uridine Monophosphate — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Uridine Monophosphate third party tested NSF
CapsulesPre-measured Uridine Monophosphate capsules — easiest for travel and consistent daily dosing without scoops or scales.Uridine Monophosphate capsules
PowderBulk unflavored Uridine Monophosphate powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Uridine Monophosphate powder unflavored
Best sellersMost-purchased Uridine Monophosphate products on Amazon — a quick way to see what's reviewed widely before you commit.Uridine Monophosphate best sellerScientific evidence8Show studiesHide studies
Souvenaid medical food in early AD
Scheltens P, et al.
12-week DB-RCT in 225 mild AD patients.
Improved memory performance vs control.
PubMed: Uridine Monophosphate — Improves cognition in MCI when stacked with omega-3 + choline
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