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Compound

Turkesterone

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Turkesterone. Ajuga turkestanica ecdysteroid.

How it works. Possible estrogen receptor beta agonist.

What the research supports. 1 graded claims. Strongest: May increase muscle (preclinical) (moderate).

How much to take. Typical dose: 500 mg.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Creatine monohydrate, Whey or EAAs.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Turkesterone. Anecdotes are not medical advice.

Turkesterone. Ajuga turkestanica ecdysteroid.

Molecular structureC27H44O8 · 496.6 g/mol

What it is

Ajuga turkestanica ecdysteroid.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Muscle Growth

How it works

Possible estrogen receptor beta agonist.

Pathways

  • Possible estrogen receptor beta agonist

Effects

  • +May increase muscle (preclinical) supports

What the research supports

May increase muscle (preclinical)moderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
500 mg
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith a meal containing fat for fat-soluble compounds; otherwise either.
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • GI upset

Medication interactions

Prescription medications (general)minor

Always disclose Turkesterone use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Creatine monohydrateFoundational support for strength, power, and lean mass.
  • Whey or EAAsProvides amino acid substrate for muscle protein synthesis.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Turkesterone — May increase muscle ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Turkesterone and "May increase muscle". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Turkesterone — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Turkesterone and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Turkesterone — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Turkesterone and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

Discussion

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