Stinging Nettle Leaf
Affiliate link: we may earn a commission at no extra cost to you. Disclosures
Stinging Nettle Leaf. Urtica dioica leaf for allergies and joint pain.
How it works. Inhibits histamine; modulates NF-κB.
What the research supports. 1 graded claims. Strongest: Reduces allergic rhinitis (moderate).
How much to take. Typical dose: 300 mg freeze-dried.
Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.
Stacking. Pairs well with Vitamin D3 + K2, Zinc.
Common forms. Available as Standardized extract capsule, Liquid tincture (alcohol or glycerin), Powdered whole herb, Traditional decoction or tea.
Key studies. 8 studies cited. The strongest are listed with links to PubMed.
Community. Experiences from people who have tried Stinging Nettle Leaf. Anecdotes are not medical advice.
Stinging Nettle Leaf. Urtica dioica leaf for allergies and joint pain.
What it is
Urtica dioica leaf for allergies and joint pain.
Food sources
Goals
How it works
Inhibits histamine; modulates NF-κB.
Pathways
- Inhibits histamine
- modulates NF-κB
Effects
- ↓allergic rhinitis decreases
What the research supports
Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.
As an Amazon Associate I earn from qualifying purchases. Look for USP, NSF or Informed Sport seals before you buy.
Side effects & interactions
Common side effects
- GI upset
Medication interactions
Always disclose Stinging Nettle Leaf use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.
Check any supplement–medication combination with your pharmacist before starting.
Combines with
Pairs well
- Vitamin D3 + K2Foundational immune modulation.
- ZincRequired cofactor for innate and adaptive immune function.
Common forms
- Standardized extract capsule
- Liquid tincture (alcohol or glycerin)
- Powdered whole herb
- Traditional decoction or tea
Key studies
8 studies cited in total.
Opens current human and preclinical literature matching Stinging Nettle Leaf and "Reduces allergic rhinitis". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Stinging Nettle Leaf and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.
Opens current human and preclinical literature matching Stinging Nettle Leaf and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.
Discussion
Loading discussion…