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evidence · mechanism · dose
Supplements/Compound

Stevia (Rebaudioside A)

Non-caloric sweetener that may improve glycemia and BP.

Blood Sugar Management

Overview

Non-caloric sweetener that may improve glycemia and BP.

Natural sources
    Common forms

      Mechanism of action

      Steviol glycosides act as TRPM5 modulators and may improve β-cell function.

      Pathways

        Effects on the body

        Organ system effects

        Evidence-based benefits

        Modest reduction in post-meal glucose

        Moderate evidence

        Potential side effects

        Common
        • · Bitter aftertaste
        Rare
          Serious

            Drug interactions

            No notable interactions reported.

            Supplement interactions

            Pairs well with

            None listed.

            Avoid combining with

            No specific avoidances listed.

            Dosing & bioavailability

            Typical dose
            200–1000 mg/day stevioside

            Where to buy

            Affiliate-style search links to reputable retailers. We don't endorse specific brands — verify third-party testing (USP, NSF, Informed Sport) before purchase.

            Compound
            Stevia (Reba…
            Amazon
            Wide selection · fast shipping
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            iHerb
            Global delivery · curated brands
            Compound
            Stevia (Reba…
            Thorne
            Practitioner-grade · NSF tested

            Scientific evidence (8)

            RCTClin Ther · 2003

            Stevioside in hypertension

            Hsieh MH, et al.

            2-year DB-RCT in 174 HTN patients.

            Key findings

            Significant reduction in SBP/DBP vs placebo.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Stevia (Rebaudioside A) — Modest reduction in post-meal glucose

            Live PubMed search

            Live results for "Stevia (Rebaudioside A) Modest reduction in post-meal glucose" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Stevia (Rebaudioside A) and "Modest reduction in post-meal glucose". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Stevia (Rebaudioside A) — randomized controlled trial

            Live PubMed search

            Live results for "Stevia (Rebaudioside A) randomized controlled trial" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Stevia (Rebaudioside A) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Stevia (Rebaudioside A) — meta-analysis

            Live PubMed search

            Live results for "Stevia (Rebaudioside A) meta-analysis" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Stevia (Rebaudioside A) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Stevia (Rebaudioside A) — pharmacokinetics

            Live PubMed search

            Live results for "Stevia (Rebaudioside A) pharmacokinetics" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Stevia (Rebaudioside A) and "pharmacokinetics". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Stevia (Rebaudioside A) — safety adverse events

            Live PubMed search

            Live results for "Stevia (Rebaudioside A) safety adverse events" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Stevia (Rebaudioside A) and "safety adverse events". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewPubMed (NLM) · 1970

            PubMed: Stevia (Rebaudioside A) — dose response

            Live PubMed search

            Live results for "Stevia (Rebaudioside A) dose response" across the PubMed/MEDLINE peer-reviewed index.

            Key findings

            Opens current human and preclinical literature matching Stevia (Rebaudioside A) and "dose response". Filter by RCT, meta-analysis, or year on the results page.

            Open study
            Systematic reviewGoogle Scholar · 1970

            Google Scholar: Stevia (Rebaudioside A) — clinical evidence

            Live Scholar search

            Cross-database citation index for Stevia (Rebaudioside A) as it relates to "clinical evidence".

            Key findings

            Includes preprints, theses, and journal articles. Useful for tracking citation counts and follow-on work.

            Open study
            Educational use only. This profile is not medical advice. Consult a qualified healthcare professional before starting any supplement, especially if you take prescription medication or have a chronic condition.