Overview
Non-caloric sweetener that may improve glycemia and BP.
- Endogenously produced or biosynthesized molecule
- Standardized pharmaceutical- or food-grade supplement
- Combined with cofactors that improve absorption or activity
- Capsule or softgel
- Powder
- Sublingual or buccal
- Liposomal liquid
Mechanism of action
Steviol glycosides act as TRPM5 modulators and may improve β-cell function.
- · Steviol glycosides act as TRPM5 modulators
- · may improve β-cell function
Effects on the body
Organ system effects
Evidence-based benefits
Modest reduction in post-meal glucose
Moderate evidencePotential side effects
- · Bitter aftertaste
Drug interactions
Supplement interactions
- A high-quality multivitaminCovers micronutrient cofactors that support most supplement pathways.
- Omega-3 (EPA/DHA)Foundational anti-inflammatory support that complements most regimens.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
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Scientific evidence8Show studiesHide studies
Stevioside in hypertension
Hsieh MH, et al.
2-year DB-RCT in 174 HTN patients.
Significant reduction in SBP/DBP vs placebo.
PubMed: Stevia (Rebaudioside A) — Modest reduction in post-meal glucose
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Google Scholar: Stevia (Rebaudioside A) — clinical evidence
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