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Spirulina (Extra Profile)

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Spirulina (Extra Profile). Cyanobacterium with phycocyanin for allergy and immunity.

How it works. Phycocyanin inhibits COX-2 and histamine release; antioxidant via free-radical scavenging.

What the research supports. 1 graded claims. Strongest: Reduces allergic rhinitis symptoms (moderate).

How much to take. Typical dose: 2 g.

Side effects and interactions. 1 medication interaction listed. No serious side effects listed at normal doses.

Stacking. Pairs well with Vitamin D3 + K2, Zinc.

Common forms. Available as Capsule or softgel, Powder, Sublingual or buccal, Liposomal liquid.

Key studies. 8 studies cited. The strongest are listed with links to PubMed.

Community. Experiences from people who have tried Spirulina (Extra Profile). Anecdotes are not medical advice.

Spirulina (Extra Profile). Cyanobacterium with phycocyanin for allergy and immunity.

Key compound: phycocyanobilinC33H38N4O6 · 586.7 g/mol

What it is

Cyanobacterium with phycocyanin for allergy and immunity.

Food sources

Endogenously produced or biosynthesized moleculeStandardized pharmaceutical- or food-grade supplementCombined with cofactors that improve absorption or activity

Goals

Immune Function

How it works

Phycocyanin inhibits COX-2 and histamine release; antioxidant via free-radical scavenging.

Pathways

  • Phycocyanin inhibits COX-2
  • histamine release
  • antioxidant via free-radical scavenging

Effects

  • ↓allergic rhinitis symptoms decreases

What the research supports

Reduces allergic rhinitis symptomsmoderate

Strong: consistent results across large trials or meta-analyses. Moderate: several trials, mostly positive. Limited: small or mixed studies. Preclinical: animal or cell research only.

Typical dose
2 g
TimingConsistent daily timing recommended; split larger doses if GI tolerance is a concern.
With foodWith meals
Best formMost evidence is based on the capsule or softgel form.
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Side effects & interactions

Common side effects

  • GI upset

Medication interactions

Prescription medications (general)minor

Always disclose Spirulina (Extra Profile) use to your prescriber — additive, antagonistic, or pharmacokinetic interactions are possible.

Check any supplement–medication combination with your pharmacist before starting.

Combines with

Pairs well

  • Vitamin D3 + K2Foundational immune modulation.
  • ZincRequired cofactor for innate and adaptive immune function.

Common forms

  • Capsule or softgel
  • Powder
  • Sublingual or buccal
  • Liposomal liquid

Key studies

8 studies cited in total.

PubMed: Spirulina (Extra Profile) — Reduces allergic rhinitis symptoms ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Spirulina (Extra Profile) and "Reduces allergic rhinitis symptoms". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Spirulina (Extra Profile) — randomized controlled trial ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Spirulina (Extra Profile) and "randomized controlled trial". Filter by RCT, meta-analysis, or year on the results page.

PubMed: Spirulina (Extra Profile) — meta-analysis ↗
Systematic review · PubMed (NLM) · 2026

Opens current human and preclinical literature matching Spirulina (Extra Profile) and "meta-analysis". Filter by RCT, meta-analysis, or year on the results page.

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