Overview
Russian anxiolytic peptide based on tuftsin.
- Synthetic peptide manufactured to pharmaceutical or research-grade purity
- Subcutaneous injection, sublingual, or oral preparation depending on bioavailability
- Compounded by a licensed pharmacy for clinical use
- Subcutaneous injection
- Oral or sublingual lozenge
- Nasal spray
- Compounded topical
Mechanism of action
Modulates GABA receptors and BDNF expression.
- · Modulates GABA receptors
- · BDNF expression
Effects on the body
Organ system effects
Selank modulates monoaminergic and GABAergic tone relevant to mood and anxiety regulation.
Evidence-based benefits
Reduces anxiety without sedation
Moderate evidencePotential side effects
- · Nasal irritation
Drug interactions
Safety & non-supplemental interactions
Educational summary — always confirm with your clinician or pharmacist before starting, stopping, or combining with prescription therapy.
- ·Pregnant or breastfeeding (insufficient safety data)
- ·Children under 18 (unless directed by a clinician)
- ·Most research peptides are not FDA-approved for human use outside investigational protocols.
Supplement interactions
- Omega-3 (EPA/DHA)Membrane fluidity and neuronal signaling support.
- Alpha-GPC or CDP-cholineProvides choline substrate for acetylcholine synthesis.
No specific avoidances listed.
Dosing & bioavailability
Where to buy
Affiliate links — we may earn a commission at no extra cost to you. Amazon code supplementsch-20 is auto-applied at checkout. We don't endorse specific brands; verify third-party testing (USP, NSF, Informed Sport) before purchase.
Third-party testedIndependently verified Selank — look for USP, NSF, or Informed Sport seals on the label for purity and dose accuracy.Selank third party tested NSF
CapsulesPre-measured Selank capsules — easiest for travel and consistent daily dosing without scoops or scales.Selank capsules
PowderBulk unflavored Selank powder — best cost-per-gram and flexible dosing for stacking or mixing into drinks.Selank powder unflavored
Best sellersMost-purchased Selank products on Amazon — a quick way to see what's reviewed widely before you commit.Selank best sellerScientific evidence8Show studiesHide studies
Selank for GAD
Zozulia AA, et al.
62 GAD patients
Comparable to medazepam without side effects.
PubMed: Selank — Reduces anxiety without sedation
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PubMed: Selank — randomized controlled trial
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PubMed: Selank — meta-analysis
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PubMed: Selank — pharmacokinetics
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PubMed: Selank — safety adverse events
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PubMed: Selank — dose response
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Google Scholar: Selank — clinical evidence
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